Whenever we put up information on alternative
treatments that have not been properly/Scientifically tested, we receive
a few angry emails.
Vitamin C and cancer.
Vitamin C and
cancer: The irrefutable evidence
Based on the research evidence, Vitamin C should
by now have achieved medical respectability both in the prevention and
treatment of cancer. Hundreds of research studies published during the
past decade alone attest to the monumental research effort mobilized to
document the role of Vitamin C in Cancer prevention and treatment.1 Numerous
books each replete with hundreds of references, have been published over
the years,2-8 documenting the vital role played by Vitamin C in every
body system function. For Vitamin C is a potent antioxidant, immune modulator,
integral to countless metabolic, endocrine and neurological functions,
and an absolute requirement for the synthesis of collagen, vital for skin,
bone, muscle and connective tissue.
The next thing [the judge] is going to say to me is, "Look, I am an educated man and I wouldn't presume to decide between Linus Pauling and the Mayo Clinic. Here is a Nobel prize winning biochemist and here are fifteen doctors from the world's leading something and one tells me yes and the other tells me no, and how the hell as I going to decide? I don't know anything about biochemistry." So he will say, "Look Mr [Attorney], you make a very interesting and persuasive argument, but on the other hand Mr. ______ over here makes a very persuasive argument and I mean isn't this a question for scientists to decide? The history of science for a thousand years is that someone comes up with an idea, the establishment ridicules him, then fifty years later they find he was right and he becomes a saint. That's just life, and Pauling is in the great tradition of outcasts." That's if I had a good judge. The worst is if I had a bad judge. He'd say, "Look, Pauling is not a doctor – these guys are doctors; that's enough for me." That could happen.
An Attorney's Advice to Linus Pauling at the height
of the vitamin C and cancer controversy (Linus Pauling Institute) March,
Mechanisms of Vitamin C's Anti-Cancer Abilities
1 Scavenges cancer-causing free radicals such as
hydrogen peroxide to prevent lipid peroxidation and destruction of cells;
Protection from Cancer
* An analysis by G Block, University of California,
of 90 epidemiological studies which examined the role of vitamin C or
vitamin-C-rich foods showed that the vast majority found statistically
significant protective effects. Evidence was "strong" for cancers
of the esophagus, oral cavity, stomach, and pancreas; "substantial"
for cervical, rectal and breast cancers as well as recent evidence for
the role of Vitamin C in lung cancer.11
Treatment in Cancer
* Lupulescu, Wayne State University, Detroit studying
the inhibition of cancer cell metabolism and proliferation by Vitamin
C upon rat tumour (basal and squamous) cells at the ultrastructural and
cell surface level, revealed cell cytolyis (disintegration), disorganization,
mitochondrial alterations, cell membrane disruption and increased collagen
Back to the Real World of Oncology Practice
Vitamin C Shields Cells
Sure they're tasty, but there's another reason that you might want to down a glass of freshly squeezed orange juice, slice a red pepper over your green salad and nibble a handful of fragrant strawberries. You'll be getting lots of vitamin C, potentially potent protection against cancer.
"Approximately 90 population studies have examined the role of vitamin C-rich foods in cancer prevention, and the vast majority have found statistically significant protective effects," reports researcher Gladys Block, Ph.D., of the University of California, Berkeley. "Evidence is strong for cancers of the esophagus, oral cavity, stomach and pancreas. There is also substantial evidence of a protective effect against cancers of the cervix, rectum and breast."
One review that looked at the results of several population studies found that women with the lowest risk of breast cancer were getting about 300 milligrams of vitamin C a day, the equivalent of about 4½ oranges or about three cups of orange juice. Their risk was reduced by about 30 percent.
In a study from Latin America, an area with one of the highest rates of cervical cancer in the world, women who got more than 314 milligrams of vitamin C a day had 31 percent less risk of developing cervical cancer than women whose intakes were under 153 milligrams a day.
And in a study from New Orleans, people getting at least 140 milligrams of vitamin C in their diets (about two oranges' worth) every day were only half as likely to develop lung cancer as those getting less than 90 milligrams a day.
"Vitamin C is a potent antioxidant," explains Balz Frei, Ph.D., associate professor of medicine and biochemistry at Boston University School of Medicine.
What's an antioxidant?
"Vitamin C," explains Dr. Frei, "along with certain other nutrients, has the ability to neutralize free radicals, harmful molecules in the body that can be produced during chemical reactions that involve oxygen."
Free radicals steal electrons from your body's healthy molecules to balance themselves, and in the process, they can harm a cell's membrane and genetic material. Antioxidant nutrients such as vitamin C offer free radicals their own electrons and so save cells from oxidative damage. "Free radical damage can occur as the result of normal body processes as we age and can also be the result of exposure to cancer-promoting chemicals," Dr. Frei explains.
Vitamin C helps prevent mouth, throat, stomach and intestinal cancers by neutralizing cancer-promoting nitrosamines. Nitrosamines are produced during the digestion of nitrites and nitrates. Nitrites are preservatives found in especially high concentrations in meats such as hot dogs and ham, while nitrates are naturally present in vegetables.
Vitamin Chelps maintain a healthy immune system, an additional cancer-fighting talent. Plus it may help build up vitamin E, another anti-cancer nutrient, to proper fighting form.
Most experts believe that the average daily intake of vitamin C, 109 milligrams for men and 77 milligrams for women, isn't enough to provide optimum cancer protection. Although vitamin Csupplements can easily boost your intake, eating vitamin C-rich foods such as citrus fruits and other tropical fruits, broccoli and brussels sprouts provides additional cancer protection with nutrients such as folate(the naturally occurring form of folic acid), beta-carotene, bioflavonoidsand fiber. In fact, evidence of anti-cancer activity is considerably stronger for vitamin C-rich fruits and vegetables than for vitamin C itself.
The amounts of vitamin C supplementation that doctors recommend to optimize the potential for cancer protection vary widely, from 50 to 5,000 milligrams or more a day. Most, however, stay within 250 to 1,000 milligrams a day, taken in two or three divided doses.
Prescriptions for Healing
Some doctors recommend these nutrients, in a range of amounts, as part of a program to prevent or treat cancer.
Vitamin C (ascorbic acid)--has a chemotherapeutic
effect on many cancers, promotes collagen production, sequestering the
tumor, and reduces the toxicity of conventional therapies
Various clinics are using intravenous vitamin C and with positive results. Dr. Hugh Riordan, recognized as a world authority on this procedure, practices from Wichita, KS, at the Center for the Improvement of Human Functioning International. Dr. Riordan's vitamin C story began in 1984 when he treated his first cancer patient; a 70-year-old renal cell carcinoma patient with metastasis to the lung and liver, using injectable vitamin C. Renal cell carcinoma has only a 5% response rate.
The initial treatment began with 15 grams of vitamin C administered intravenously 2 times a week; showing excellent tolerance, the vitamin C dosage was increased to 30 grams twice weekly. Within 6 weeks, the patient showed a favorable response to treatment and at the 12-week interval was pronounced tumor-free. The patient lived 14 additional years and died of congestive heart failure with no evidence of tumors.
In light of the favorable initial response to intravenous (IV) vitamin C, ascorbic acid was investigated. Vitamin C is preferentially toxic to tumor cells, that is, it kills tumor cells but not normal cells.
In low doses, vitamin C assumes the nature of an antioxidant; in high dosages, vitamin C changes roles and becomes a prooxidant, inducing peroxide production. Tumor cells have a relative catalase deficiency, an enzyme necessary to detoxify hydrogen peroxide to water and oxygen. A 10- to 100-fold difference in catalase concentrations exists between tumor cells and normal cells. Without the protection of catalase, peroxide accumulates in cancerous cells, along with aldehydes (toxic byproducts of the reaction), causing death to malignant cells. On the other hand, normal, healthy tissues have the protection of the detoxification enzyme and are spared destruction by peroxide and aldehyde. Vitamin C, a virtually nontoxic nutrient (Bowie et al. 2000), could cause a transient diarrhea if not absorbed properly.
Vitamin C is safe compared to standard chemotherapeutics and has an ability to preserve immune function. Many patients succumb, not because of cancer, but rather from a post-chemotherapeutic toxicity, resulting from a damaged immune system. Vitamin C protects the immune system. Vitamin C is preferentially toxic to many types of cancer cells, including 20 different melanoma cell lines. Ovarian cell lines are more susceptible to vitamin C-induced toxicity than pancreatic cells. Breast cancer appears to be one of the most responsive cancers to IV vitamin C.
Much higher concentrations of vitamin C are required to kill cancer cells than originally thought, about 600 mg/dL. Also, as the density of the cells increases, the efficacy of vitamin C decreases. It is extremely difficult to reach vitamin C concentrations greater than 200 mg/dL even when administered intravenously (Riordan et al. 2000). To increase the sensitivity of tumor cells to vitamin C, other approaches need to be employed.
Alpha-lipoic acid, a water- and lipid-soluble antioxidant that recycles vitamin, enhances the toxic effect of ascorbic acid. Lipoic acid decreases the dose of vitamin C required to kill tumor cells from 700 to 120 mg/dL (Riordan et al. 2000). Vitamin C toxicity is further enhanced by 1000 mcg of vitamin B12, which forms cobalt ascorbate, a benign but cancer-cell-toxic agent. Vitamin K, selenium, quercetin, niacinamide, biotin, and grape seed extract are also regarded as potentiation factors.
The goal is to achieve and maintain 400 mg/dL of vitamin C in the plasma. At this concentration, every cancer cell line so far tested has been found to be sensitive to vitamin C. After reaching an ascorbic acid peak, as occurs during infusion, the level returns to near baseline levels 24 hours after the IV infusion.
Vitamin C has an ability to increase collagen production. Vitamin C is required for the hydroxylation of proline, which in turn is required for collagen production. Vitamin C has the ability to inhibit enzymes that degrade or break down the extracellular matrix. Vitamin C dramatically increased the collagen within tumor cells, an act that tended to immobilize the cells
Vitamin C (supported by lipoic acid) has been used as a cancer therapy. It is strongly advised that patients contact a physician trained in administering infusions and monitoring progress. By giving vitamin C intravenously, doctors can achieve a blood saturation that far exceeds that attained by administering vitamin C orally (200% versus 2%). A high dose of vitamin C is critical to achieve tumor cell kill.
A Hickman line allows large doses of vitamin C to be self-administered at home on a daily to weekly basis over a period of months, modulating down or up in frequency according to response. Otherwise the treatment can be administered as an outpatient. Contraindications to vitamin C therapy are few but include individuals with kidney failure and on dialysis, as well as those with hemochromatosis. Also, physicians should screen patients for a red blood cell glucose-6 phosphate dehydrogenase deficiency, a rare condition whose presence can lead to a hemolytic crisis involving red blood cell breakdown.
Large doses of vitamin C should be reached gradually to establish tolerance. For example, 15 grams for one or two sessions and then 50 grams to 100 grams if necessary. The exact dose is determined by the individual's plasma saturation immediately after an infusion. The therapy should not be stopped abruptly because a rebound effect could result in scurvy. Patients should allow weeks or even months to wean off the treatment, with oral vitamin C therapy used on the days between infusions.
A 10-year research project using high dose IV vitamin C has been completed. While a number of orthomolecular physicians are using IV vitamin C therapy, it is recommended that Dr. Riordan's protocol become the backbone of the therapy. Instructions are available to physicians upon request from the center (Riordan et al. 2003).
Center for the Improvement of Human Functioning
Other chemotherapeutic credits awarded to vitamin C:
Vitamin C prolongs the lives of animals undergoing
conventional cancer treatment by protecting normal cells against chemotherapy-induced
toxicity; in tandem, vitamin C increases the cytotoxicity targeted at
the cancer (Antunes et al. 1998; Giri et al. 1998). When 5-FU was administered
together with vitamin C, the tumor cell kill rate was boosted from 38
to 95.5%. X-ray therapy decreased cancer growth 72%, but adding vitamin
C to the regime decreased cancer growth by 98.2%. Full spectrum antioxidants
rather than isolated nutrients are suggested (Prasad et al. 1999; Moss
1. Nutrition and Cancer Database is a comprehensive
compilation of published scientific research, with Abstracts. 1993. For
information, contact the Bristol Cancer Help Centre (0272) 743 216.
Alpha Lipoic Acid 200mg 60t SN 0395 $24.05
Beta Carotene SN0403 $14.44
beta glucan 30t SN1758 $31.11
Bromelain 600Gdu-Gm 500mg 60T SN0906 $13.23
EllargicActive 30 SN1629 $23.11
Essential Enzymes 60c SN0659 $14.85
Essential Fatty Acids 60 SN1384 $19.13
Essential Fatty Acids 120 SN1385 $29.72
Feverfew 100t SN 0209 $19.13
Inositol Hex 100gr SN1366 $19.52
Inositol Hex 200gr SN 1367 $30.11
Cordyceps 60t PF0432 $15.56
L- Arginine 100t SN 1279 $16.68
L- Arginine 200t SN1688 $24.41
Life Force 60t SN765 $29.95
L-Lysine 500mg 100T SN0139 $12.58
L-Selenomethionine 60T SN0922 $12.58
Lycopene 15mg 30sg SN1290 $21.98
Modified Citrus Pectin pwd 100gr SN $34.19
Modified Citrus Pectin pwd 200gr SN0702 $56.19
MSM 60t 1000mg SN1288 $15.09
NAC 100t 1000mg SN0169 $24.83
NAC 100t 600mg SN0850 $17.84
NAC 200t 600mg SN0967 $26.31
NAC 200t 1000mg SN0170 $39.89
Niacin 100mg 100T SN0501 $10.70
Optizinc Zinc Monomthn 30mg 60T SN0847 $11.37
Potasium Iodide 32.5mg 60t SN1623 $14.83
Potassium Chelated 99mg 100T SN0320 $12.06
Quercetin 100t SN1690 $35.90
Quercetin 50t SN1689 $22.42
Co -Q10 100mg 60c
Resveratrol 60t 500mg SN1011 $32.36
Resveratrol 30t 500mg SN1010 $21.08
Saw Palmetto Extract 160mg 60sg SN0441 $16.25
Theanine Serene 60t SN1775 $19.52
Thymus Extract 20t SN1519 $48.04
Tonalin 60 SN0949 $22.39
Tonalin 90 SN1537 $27.67
Transfer Factor SN1815 $16.32
Tumeric Extract 95% Curcim 100t SN0089 $23.42
Tumeric Extract 95% Curcim 50t SN0088 $19.87
Vit A 200t SN 1792 $14.96
Vit A 100t SN0828 $10.69
Vit C 16oz SN0092 $30.98
VIT D 100t SN1791 $11.37
VIT D 200t SN1792 $14.09
Vit E Succinate 400iu 100T SNO482 $20.88
Vit K 100t SN1449 $12.41
Vit K 200t SN1450 $16.26
Wellness Formula 45T SN0021 $21.08
Ginger PF0417 $19.83
|Cancer cells hide after Chemotherapy
After the initial doses of radiation and/or chemotherapy, cancer cells start hiding.
" They develop a slime coating, and they become like Stealth bombers, and they can hide from future doses of radiation and chemotherapy. This is why repeated dose of radiation and chemotherapy become less effective".Dr. John Maras, Nu-Gen Educational Library.
" The way to get rid of this "slime coating" is to use large doses of plant and animal enzymes- especially bromelain and pancreatin. This allows an 'access point' for the immune system to attack the cancer cells".....Dr. John Maras, Nu-Gen Educational Library
What doctors say about Chemo Therapy ?
"The world is a dangerous place to live; not because of the people who are evil, but because of the people who don't do anything about it."
A Sad day for Alternative healing
|NOTICE: Due to FDA TGA MOH (plus other institutions with a vestige interest) regulations and various state laws, no medical claims can be made for alternative therapys and technology. All of the information expressed herein must be considered theoretical and unproven and for experimental research only|
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