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Oxygen
OXYGEN, OZONE, & HYDROGEN PEROXIDE
Majid Ali, M.D.
(Abridgement from The Journal of Integrative Medicine Article: Oxidative Regression To Primordial Cellular Ecology (ORPEC))

The author's clinical experience has led him to conclude that oxygenative antioxidant therapies such as nasal oxygen and intravenous infusions of ozone-oxygen gas mixture and hydrogen peroxide are among the most beneficial therapies for reversing the ORPEC state.

Since oxygen, ozone and hydrogen peroxide act as oxidants in a laboratory setting, therapies employing those agents are generally deemed oxidative therapies.191-193 Until recently, the author accepted that view uncritically. However, it is clear from studies presented in this article that this is a gross error. In reality, such therapies in the context of the ORPEC state are powerful oxygenative and antioxidant therapies. The reason for that widespread misconception is the failure to clearly understand the complex biologic consequences of adding oxygen, ozone, and hydrogen peroxide to severely impaired enzymatic and cellular ecosystems in patients with accelerated oxidative injury.

A Burst of Thunderstorm, A Burst of Oxidants

An analogy of a burst of thunderstorm may be used to explain the possible mechanism action of ozone. The still air in a city on a hot, humid summer afternoon is thick with stagnant smog. The traffic on city streets is snarled. Tree leaves are dry and limp. Many persons are distressed by air pollution. Suddenly, dark clouds loom large and bring a heavy thunderstorm. Strong winds push out the polluted air. Tree leaves are bombarded by heavy rains. The healthy and robust leaves of trees withstand the storm well, while older and weakened leaves are severely damaged. Many withering leaves on tree brances are blown away. After the thunderstorm subsides, the air is clean and crisp. The trees looked washed, their leaves fresh and shiny. Bursts of intravenously injected ozone and hydrogen peroxide affect the blood elements the same way. The membranes of healthy erythrocytes withstand the oxidative stress of ozone and hydrogen peroxide well, recovering their normal morphology after initial membrane deformities. The senescent cells, by contrast, shrink and undergo lysis.

Below, some theoretical, clinical and experimental considerations are presented that shed light on the apparent paradox of agents that are oxidizing in their essential roles, and yet provide the basis for oxygenative antioxidant therapies.

Intermittent Nasal Oxygen

The oxygenative role of nasal oxygen is self-evident. Oxygen is also a powerful oxidizer, as discussed earlier in the section devoted to spontaneity of oxidation in nature. The ORPEC hypothesis provides a clear scientific basis for oxygen's ability to also serve the opposing antioxidant role. As discussed earlier, anoxia increases oxidative stress directly by facilitating the generation of toxic reactive species as well as indirectly by causing acidosis.

In this author's clinical experience, the use of intermittent nasal administration of oxygen (2.5 to 3.5 L/min given for periods of one hour two or three times a day) benefits most patients in the ORPEC state. It is also the opinion of the author that oxygen therapy is very underutilized in the care of patients in the ORPEC state, such as those with fibromyalgia, chronic fatigue state, severe autoimmune disorders, and spreading malignant tumors. Oxygen is readily and inexpensively available to all patients. Also available are inexpensive portable rental units that may be used in travel as well.

When used intermittently and in moderate doses as described here, this therapy has been found to be completely free of adverse effects. The author also has limited experience with oxygen therapy in patients with severe pulmonary emphysema and pulmonary interstitial fibrosis. Evidently, the use of oxygen in such patients must be monitored closely so that oxygen therapy does not cause further deterioration in the function of central sensors for oxygen and carbon dioxide.

Intravenous Ozone Therapy

Ozone is triatomic oxygen with a high electrovoltaic potential. Ozone gas infused intravenously at the Institute consists of a gaseous mixture with oxygen containing a very low concentration of ozone. It is prepared by passing pure oxygen through a high voltage field. The concentration of ozone generated depends on the rate of flow of oxygen as well as on the conditions of voltage and spacing of electrodes. The gaseous mixture used in our clinical practice is titrated to contain from 0.3 to 2.5% (30 to 50 ug O3/ml O2). Thus, intravenously administered "ozone" in reality represents 97 to 99.7% of pure oxygen.

Practitioners who have never administered ozone gas mixture intravenously often express concern about the possibility of air embolism caused by gas infusion. Such concern is totally unwarranted. Pure oxygen and ozone diffuse immediately into the blood and do not persist as gases. The author has tested for that on numerous occasions by injecting 2 ml of the ozone mixture into a large vein, then immediately drawing the blood back. Except on uncommon occasions, the blood drawn back from the vein is pink (ozone turns dark venous blood into pink blood) and free of any gas bubbles. One can safely presume that the process of dissolution of the gas mixture would be complete by the time it reaches the large veins in the thorax.

Another concern expressed by those unfamiliar with the clinical uses of ozone mixture is the toxicity of ozone as discussed by environmentalists. It must be recognized that those individuals are perturbed by the products of reaction of ozone with other ecopollutants such as oxides of nitrogen. Ozone is a highly reactive molecule. Indeed, ozone owes its many antiviral, antibacterial, and antifungal properties to this aspect of this specific aspect.

Microscopic Evidence for the Antioxidant Role of Intravenous Ozone Therapy

In the concentration used our in clinical practice, ozone causes temporary and reversible erythrocyte membrane damage as evidenced by clumping and red cell membrane deformity. The evidence for the oxidative nature of such erythrocyte membrane deformities has been previously demonstrated by the reversibility of such changes with antioxidants such as ascorbic acid, tocopherol, and taurine.56,57

How may the observed overall invivo antioxidant effects of ozone, a powerful invitro oxidant, be explained? Ozone has well established effects of improving tissue perfusion and cellular oxygenation.67 Just as the duality of oxygen allows it to be a molecular Dr. Jekyll and Mr. Hyde, reactive oxidant species also play dual roles. Not only do they inflict oxidative damage to enzymes, induce mutations, and damage cell membranes, they also serve many useful functions such as modulation of cellular redox dynamics, activation of gene transcription, signal transduction, and apoptosis.93-95 It seems that ozone evokes an upregulatory response from cell membrane-associated antioxidant enzyme systems just as all oxidants do from all biologic antioxidant systems. Though, direct quantitative data for those effects are not yet forthcoming. One may also, with good reason, speculate that ozone elicits similar responses from other matrix- and cell organelle-related antioxidant systems. There is yet an other important mechanism by which ozone protects patients with chronic illnesses from accelerated oxidative stress. Viruses, bacteria, fungi, PLFs and parasite inflict cellular injury by causing oxidative stress. Ozone also is a well established antiviral, antibacterial, and antifungal agent.58-63. Ozone through its powerful antimicrobial effects reduces the overall oxidative stress on persons with chronic viral, bacterial, fungal and PLF overgrowth syndromes. Thus, the ORPEC hypothesis carries strong explanatory power for the empirically observed biologic antioxidant effects of ozone.

Intravenous Hydrogen Peroxide Therapy for the ORPEC State

The biologic antioxidant effects of hydrogen peroxide, a potent oxidizer like ozone, are mediated by all the mechanisms cited for ozone in the preceding section. The clinical benefits of hydrogen peroxide infusions observed at the Institute in patients with fibromyalgia and chronic fatigue syndrome are the subject of a separate report.72

Reference from the complete article in The Journal of Integrative Medicine 1998;2:4-55

References

1. Ali M. Spontaneity of Oxidation in Nature and Aging. Monograph, Teaneck, New Jersey, 1983.
2. Ali M. The agony and death of cell. Syllabus of the Instruction Course of the American Academy of Environmental Medicine, Denver, Colorado, 1985.
3. Ali M. Molecular basis of cell membrane injury. In: Syllabus of the Instruction Course of the American Academy of Environmental Medicine. Denver, Colorado, 1990.
4. Ali M. Spontaneity of oxidation and chronic disease. In: Syllabus of the Instruction Course of the American Academy of Environmental Medicine, Denver, Colorado, 1992.
5. Ali M. Oxidative coagulopaty. In: Syllabus of the Capital University of Integrative Medicine, Washington, D.C., 1997.
6. Ali M. Spontaneity of oxidation in nature is the root cause of all illness. In: RDA: Rats, Drugs and Assumption. pp. 199-304. Life Span, Denville, New Jersey, 1995.
7. Ali M. Leaky cell membrane dysfunction. Monograph 1987. Teaneck, New Jersey.
8. Ali M. Oxidative plasma membrane injury and magnesium. Environmental Physician. Summer 1992. American Academy of Environmental Medicine, Denver, Colorado.
9. Ali M. Ascorbic acid reverses abnormal erythrocyte morphology in chronic fatigue syndrome. Am J Clin Pathol. 1990;94:515.
10. Ali M. Ascorbic acid prevents platelet aggregations by norepinephrine, collagen, ADP and ristocetin. Am J Clin Pathol. 1991;95:281.
11. Ali M. The basic equation of life. pp 225-236. In: The Butterfly and Life Span Nutrition. The Institute of Preventive Medicine Press, Denville, New Jersey. 1992.
12. Ali M. Spontaneity of oxidation and molecular basis of environmental illness. In: Syllabus of the 1991 Instruction Course of the American Academy of Environmental Medicine, Denver, Colorado, 1990.
13. Ali M. The Ghoraa and Limbic Exercise. The Institute of Preventive Medicine Press, Denville, New Jersey. 1993.
14. Ali M. What Do Lions Know About Stress? Life Span, Denville, New Jersey. 1996.
15. Ali M. The Cortical Monkey and Healing. The Institute of Preventive Medicine, Bloomfield, New Jersey. 1989.
16. Ali M. Healing, Miracles and the Bite of the Gray Dog. Life Span, Denville, New Jersey. 1997.
17. Ali M. Hypothesis: Chronic fatigue is a state of accelerated oxidative molecular injury. J Advancement in Medicine. 1993;6:83-96.
18. Ali M. The Canary and Chronic Fatigue. 1994. Life Span, Denville, New Jersey.
19. Ali M, Ali O. AA Oxidopathy: the core pathogenetic mechanisms of ischemic heart disease. J Integrative Medicine 1997;1:1-112.
20. Des Marais DJ, Strauss H, Summons RE et al. Carbon isotope evidence for the stepwise oxidation of the Proterozoic environment. Nature 1992;359:605-609.
21. Canfield DE, Teske A. Late proterozoic rise in atmospheric oxygen concentration inferred from phylogenetic and sulphur-isotope studies. Nature 1996;382;127-132.
22. Miller SM. The origins of life on earth. 1974. Prentice-Hall, Englewood Cliffs, New Jersey.
23. Margulis L. Biodicersity: Molecular biologica; domains, symbiosis and kingdon origins. Biosystems 1992;27:39-51.
24. Carpendale MT, Griffis J. Is there a role for medical ozone in the treatment of HIV and associated infections. Monograph. Bay Medical Research Foundation 1991.
25. Carpendale MT, Freeberg JK. Ozone inactivates HIV at non-cytotoxic concentrations. Antiviral Research 1991; 16:281-292.
26. Matassi R, D'Angelo F, Franching A, et al. Ozone therapy in Herpes Simplex and Herpes Zoster diseases. In: Laraus J. ed. Medical Applications of Ozone. International Ozone Association. 1985 pp 134-139. Norwalk, CT.
27. Botstein D, Chervitz SA, Cherry JM. Yeast as a model organism. Science 1997;277:1259-1260.
28. BLASTP analysis were done between all yeast ORF translations and all unique protein sequences in the human, mouse, rat, cow, and sheep sequences in GenBank as of 22 July 1997. We used the BLOSUM62 substitution mastrix and low-complexity filters seg and xnu. "Unknown function" means that the ORF had no entry in either the Gene_Product or Description fields within its SGD Locus page as of 30 July 1997. For all ORFs, 3783 (60.8%) have unknown function by this definition. BLASTP, version 2.0a, W. Gish, unpublished data; SF Altschul, W Gish, W Miller, EW Myers, DJ Lipman. J Mol Biol 1990;215:403.
29. Beale LS. Observations upon the nature of the red blood corpuscles. Trans Microsc Soc. London 1864:12:37.
30. Magath TB. Spirochetes in the blood. Am J Clin Pathol. 1953;23:691-693.
31. Mattman LH. Cell Wall Deficient Forms: Stealth Pathogens. CRC, Boca Raton, 1992.
32. Ali M, Ali O, Bradford R. et al Immunostaining of candida organisms in peripheral smears. (Abstract). 1995. American Academy of Otolaryngic Allergy, Spring Meeting, Palm Desert, CA.
33. Ali M and Ramanarayanan MP: A computerized micro-ELISA assay for allergen-specific IgE antibodies. Am J Clin Pathol 1984;81:591.
34. Ali M, Ramanarayanan MP, Nalebuff DJ, et al: Serum concentrations of allergen-specific IgG antibodies in inhalant allergy: Effect of specific Immunotherapy. Am J Clin Pathol. 1983;80:290.
35. Ali M. Altered States of Bowel Ecology. Monograph. Life Span, Denville, New Jersey 1983.
36. Lorian V, Waluschka A. Blood cultures showing aberrant forms of bacteria. Am J Clin Pathol 1972;57:406-409.
37. Lorian V, Atkinson B. Abnormal forms of bacteria produced by antibiotics. Am J Clin Pathol 1975;64:678-688.
38. Komber KR, Boon RJ, Sutherland R. Comparative effects of amoxycillin and ampicillin on the morphology of Eschercia coli in vivo and correlation with activity. Antimicrob Agents Chemother 1977;12:736-744.
39. Nakao M, Nishi T, Tsuchiya K. In vitro and in vivo morphologic response of Klebsiella pneumoniae to cefotiam and cefazolin. Antimicrob Agens Chemother 1981;19:901-910.
40. Davis KJ, Vogel P, Fritz DL, et al. Bacterial filamentation of Yersenia pestis by B-lactam antibiotics in experimentally infected mice. Arch Pathol Lab med 1997;121:865-8. -induced
41. Dwyer JJ, Burnett LE. Acid based status of the oyster Crassostrea virginica in response to air exposure and to infections by Perkinsus marinus. Biol Bulletin 1996;190:139-147.
42. Knoll AH, in Origins and Early Evolution of the Metazoa (eds Lipps, JH Signor, D.W.53-84. (Plenum, New York, 1992).
43. Holland HD. The Chemistry of the Atmosphere and Oceans (Wiley, New York, 1978).
44. Knoll AH. Breathing room for early animals. Nature 1996;382:111-112.
45. Mattman LH. Cell Wall Deficient Forms: Stealth Pathogens. CRC Press, Boca Raton, Florida, 1993.
46. Henning W. Phylogenetic Systematics. University of Illinois Press, Urbana, Il.) 1966.
47. Margulis L. Symbiosis in Cell Evolution. 1992 2nd edn. WH Freeman, New York
48. Gross M. Life on the Edge:Amazing Creatures Thriving in Extreme Environment. Plenum 1998. England.
49. Saccharomyces Genome Database (SGD) at http://genome-www.stanford.edu/Saccharomyces/;Yeast Genome from MIPS (Martinsried Institute for Protein Sequences) at http://speedy.mips.biochem.mpg.de/mips/ yeast/ www.proteome. com/YPDhome.html; A. Goffeau et al., Science 1996;274:546. The Saccharomyces Genome Database is suppported by an NIH research resources grant (HG 01315).
50. Kataoka T. Cell 1985;40:19-22.
51. Miller RV. Bacterial gene swpping in nature. Scientific American 1998;January; 67-71.
52. Ali M. Oxidant injury pokes holes in cell membranes. In: The Canary and Chronic Fatigue. pp 197-205. Life Span, 1995. Denville, New Jersey.
53. Ali M. Oxidative theory of cell membrane and plasma damage. In: RDA: Rats, Drugs and Assumption. Page 281-302. 1995 Life Span, Denville, New Jersey.
54. Ali M, Ali O. Leaky cell membrane dysfunction. In: AA oxidopathy: The core pathogenetic mechanism of ischemic heart disease. pp 72-74. J Integ Medicine 1997;1:6-112.
55. Ali M. Experience with intravenous nutrient therapy for allergic patients with chronic fatigue. Am Acad Otolaryngic Allergy Abstracts Summer 1992;p23.
56. Ali M. Intravenous Nutrient Protocols in Molecular Medicine. Institute of Preventive Medicine. 1989. Bloomfield, New Jersey.
57. Ali M. Leaky cell membrane dysfunction. Monograph 1987. Teaneck, New Jersey.
58. Yusuf, S. Calcium antagonists in coronary artery disease and hypertension-Time for reevaluation? Circulation 1995;92:1079-1082.
59. Furberg CD, Psaty BM, Meyer JV. Nifedipine: Dose-related increase in mortality in patients with coronary heart disease. Circulation;92:1326-1331.
60. Boden WE, Schelewaert R, Walters EG. Design of a placebo-controlled clinical trial of long-acting diltiazem and aspirin versus aspirin alone in patients receiving thrombolysis with a first acute myocardial infarction. Am J cardiol 1995;75:1120-1123.
61. Thadani U, Zellner S, Glasser S et al. Double-blind, dose-response, placebo-controlled multicenter study of nisoldipine: a new second-generation calcium channel blocker in angina pectoris. Circulation 1991;84:2398-2408.
62. Fisher A, Bogouslaviskt J. Further evolution toward effective therapy for acute ischemic stroke JAMA;279:1298-1303.
63. Woods, KL, Fletcher S. Long-term outcome after intravenous magnesium sulphate in suspected acute myocardial infaction: The second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2). Lancet 1995;343:816-9.
64. Woods KL, Fletcher S, Roffe C, Haider Y. Intravenous magnesium sulphate in suspected acute myocardial infarction: Results of the second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2). Lancet 1992;339:1553-8.
65. Ali M. Experience with intravenous nutrient therapy for allergic patients with chronic fatigue. Am Acad Otolaryngic Allergy Abstracts Summer 1992;p23.
66. Seelig MS, Elin RJ. Reexamination of magnesium infusions in myocardial infarction. Am J cardiol 1995;76:172-173.
67. Halstead BW. The Scientific Basis of Chelation Therapy. Golden Quill Publishers, Inc. Box 1278, Colton, Ca
68. Baldridge CW, Gerald RW. The extra respiration of phagocytosis. Am J Physiol 1933;103:235.
69. Berendes H, Bridges RA, Good RA. A fatal granulomatosis of childhood. The clinical study of a new syndrome. Minn Med 1957;40:309.
70. Cohen MS, Metcalf JA, Root RK. Regulation of oxygen metabolism in human granulocytes: Relationship between stimulus binding and oxidative response using plant lectins as probes. Blood 1980;55:1003.
71. Curnutte JT, Babior BM. Biological defense mechanisms. The effect of bacteria and serum on superoxide production by granulocytes. J Clin Invest 1974;53:1662.
72. Babior BM, Kipnes RS, Curnutte JT. Biological defense mechanisms. The production by leukocytes of superoxide, a potential bacterial agent. J Clin Invest 1973;52:741.
73. Ali M. Cell Membrane Stressors. Monograph 1987
74. Virchow R. Die Cellularpathologie in ihrer Bedeutung auf physiologische und pathologische Gewebslehre. Hirschwald, Berlin 1858
75. Bordue L. Recherches sur le tissu muqueux ou l'organ cellulaire. Paris 1767, 1 and 2.
76. Reichert CB. Vergleichende Beobachtungen uber das Bindegewebe und die verwandten Gebilde. Dorpat 1845, S.168.
77. Rokitansky C. v., Handbuch der pathologischen Anatomie. Wein 1846.
78. Pischinger A. Matrix and Matrix Regulation. 1975 Haug International, Brussels.
79. Bradford R. Henry A. Oxidology. 1997. Bradford Research Institute. San Diego
80. Keidel W. Lehrbuch der Klimatologie. G. Thieme Verlag. Stuttgart 1970.
81. Nimni ME. ed. Collagen 1-4. 1988 CRC, Boca raton, Florida.
82. Berg RA, Prockop DJ. Biochem. Biophys Res Commun 1973;52:115-120.
83. Holmgren SK, Taylor KM, Bretscher LE, et al. Code of collagen's stability deciphered. Nature 1998;392:666.
84. Shaw W. Role for certain yeast and bacteria byproducts discovered by organic acid testing in the etiology of a wide variety of human diseases. Bulletin of the Great 84.
85. Sell D, Monnier V. Structure elucidation of a senescence cross-link from human extracellular matrix. Implications of pentoses in the aging process. J Biol Chem 1989;264:21597-21602.Plains laboratory. Overland Park, KS 66204
86. Shaw W. Role for certain yeast and bacteria byproducts discovered by organic acid testing in the etiology of a wide variety of human diseases. Bulletin of The Great Plains Laboratory. Overland park, KS 66204 (913) 341-8949.
87. Gupta S. Aggarawal and Heads C. Dysregulated immune system in children with autism. Beneficial effects of intravenous immune globulin on autistic characteristics. Autism Develop Dis 1996;26:439-452.
88. Nagaraj RH et al. Suppression of pentosidine formation in galactosemic rat lens by an inhibitor of aldose reductase. Diabetes 1994;43:580-6.
89. Cuatrecases P, Tell GPE. Insulin-like activity of coconcanavalin A and wheat agerm agglutinin-direct interactions with insulin receptors. Proc Natl Acad Sci USA 1973;70:485-9.
90. Erickson RH, Kim YS. Interaction of purified brush-border membrane amniopeptidase N and dipeptidase IV with lectin-Sepharose derivatives. Biochim Biophys Acta 1983;743:37-42.
91. Pischinger A. Matrix and Matrix Regulation. Haug International. 1975, Brussels, pages 69-78
92. Klotz SA. A fibronectin receptor on Candida albicans mediates adherence of the fungus to extracellular matrix. J Infectious Dis 1991;163:604-6.
93. M. Kolarova. Host-tumor relationship XXXIV. Hyaluronidase activity and hyaluronidase inhibitor in the serum of patients with malignant tumors. Neoplasma 1977;24:285.
94. Savolainen ER. Enzymes of collagen biosynthesis in diseases of the liver and connective tissues. Changes in prolyl hydroxylase and galactosylhydroxylsyl glucosyltransferase in serum and tissues. Chem Absts 1979 91:1729Ilt.
95. Alitalo K, et al. Extracellular matrix proteins characterize human tumor cell lines. International Journal of Cancer 1981;27:755.
96 Harris DA. Bioenergetics at a glance. 1995. pp84-85. Blackwell Science.
97. De Stefano N, Argov Z, Matthews PM, Karpati G, Arnold DL. Impairment of muscle mitochondrial oxidative metabolism in McArdle's disease. Muscle & Nerve 1996;19(6):764-9.Harris
98. Sjostrand FS. Electron microscopy of mitochondria and cytoplasmic double membranes. Nature (London) 1953;171:30.
99. Lindane AW, Marzuki S, Ozawa T, et al. Mitochondrial DNA mutations as an important contributor to aging and degenerative diseases. Lancet 1985;1:642-5.
100. Babcock GT, Wickstrom M. Oxygen activation and the conservation of energy in cell respiration. Nature 1992;356:301-309.harris
101. Cui L, Schinazi RF, Gosselin G, et al. Effect of beta-enantriomeric and racemic nucleoside analogues on mitochondrial functions in HepG2 cells. Implication for predicting drug hepatotoxicity. Biochemical Pharmacology. 1996;52(10):1577-84.
102. Cui L, Yoon S, Schinazi RF, et al. Cellular and molecular events leading to mitochondrial toxicity of 1-(2-deoxy-2-fluoro-1-beta-D-arabinofuranosyl)-5-iodouracil in human liver cells. J Clin Invest 1995;95(2):555-63.
103. Hickman PF, Kemp GJ, Thompson CH, Salisbury AJ, Wade K, Harris AL, Radda GK. Bryostatin 1, a novel antineoplastic agent and protein kinase C activator, induces human myalgia and muscle metabolic defects: a 31P magnetic resonance spectroscopic study. British Journal of Cancer 1995;72(4):998-1003.
104. Altschuld RA, Jung DW, Phillips RM, et al. Evidence against norepinephrine-stimulated efflux of mitochondrial Mg2+ from intact cardiac myocytes. Am J Physiol. 1994;266:H1103-11.
105. McCully KK, Sisto SA, Natelson BH. Use of exercise for treatment of chronic fatigue syndrome. Sports Medicine 1996;21(1):35-48.
106. Eisenger J, Plantamura A, Ayavou T. Glycolysis Abnormalities in Fibromyalgia. J Amr Coll Nutr 1994;13(2):144-148.
107. Wysenbeck AJ, Shapira Y, Leibovici L. Primary fibromyalgia and the chroanic fatigue syndrome. Rheumatol Int 1991;10:227-229.
108. Plioplys AV, Plioplys S. Electron-microscopic investigation of muscle mitochondria in chronic fatigue syndrome. Neuropsychobiology. 1995;32(4):175-81.
109. Vecchiet L, Montanari G, Pizzigallo E, Iezzi S, deBigontina P, Dragani L, Vecchiet J, Giamberardino MA. Sensory characterization of somatic parietal tissues in humans with chronic fatigue syndrome. Neuroscience Letters 1996;208(2);117-20.
110. Cheney PR, Davidson M, Voyles CS, Wilson S. Bicycle Ergometry with gas analysis and neuroendoctrine responses to exercise in chronic fatigue syndrome. Albany, NY 1992.
111. Mengshoel AM, Forre O, Komnaes HB. Muscle strength and aerobic capacity in primary fibromyalgia. Clin Exp Rheumatol 1990;8:475-479.
112. Plioplys AV. High dose L-Carnitine improves the chronic fatigue syndrome in a prospective cross-over study. Neuropsychobiology 1997;35:16-23.
113. Is fibromyalgia caused by a glycolysis impairment. Nutr Rev 1994;52(7):248-250.
114. Kramer TR, Burri BJ. Modulated mitogenic proliferative responsiveness of lymphocytes in whole blood cultures after low carotene diet and mixed carotenoid supplementation in women. Am J Clin Nutr 1997;65:871-5.
115. Kuratsune H, Yamaguti K, Takahashi M, Misaki H, Tagawa S, Kitani T. Acycarnitine deficiency in chronic fatigue syndrome. Clin Inf Dis 1994; Volume 18, Suppl 1:562-67.
116. Rengisson A, Henriksson KG. The muscle in fibromyalgia - a review of Swedish studies. J Rheumatol 1989;16:144-149.
117. Schwartz, et al. SPECT imaging of the brain: Comparison of findings in patients with chronic fatigue syndrome, AIDS dementia complex and major unipolar depression. American Journal of Radiology. 1994 April;162.
118. Stevens SR. Using exercise testing to document functional disability in CFS. Journal of Chronic Fatigue Sundrome 1995;1 Numbers 3/4:127-129.
119. Trounce I, Byrne E, Marzuki S. Decline in skeletal muscle mitochondrial respiratory chain function: a possible factor in ageing. Lancet 1989;I(8639):637-638.
120. Wong R, Lepaschuk G, Zhu G, Walker D, Catelliger D, Burton D, Teo K, Collins-Nakaj R, Motague T. Low levels of cellular ATP following muscle exhaustion in vivo by phosphorus NMR in chronic fatigue syndrome. Chest 1992;102:1716-1722.
121. Ali M. Fibromyalgia: On The Moustache of a Mouse, (Work in progress). Life Span, Denville, New Jersey
122. Ali M. Oxidative coagulpathy and oxidative oxidopathy: Two core pathogenetic mechanisms of fibromyalgia. J Integrative Medicine. (in press).
123. Bradford coagulative and complement.
124. Rudel T, Bokoch G. Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2. Science 1997;276:1571.
125. Xu DG, et al. Elevation of neuronal expression of NAIP reduced ischemic damage in the rat hippocampus. Nature Medicine 1997;3:997.
126. Vander Heiden MG, et al. Bci-xL regulates the membrane potential and volume homeostasis of mitochondria. Cell 1997;91:627.
127. Kothakota S, et al. Caspase-3-generated fragment of gelsolin: Effector of morphological change in apoptosis. Science 1997;278:294.
128. Research News. Death by Dozens of Cuts. Science 1995;280:32-34.
129. McGregor NR, Dunstan RH, Zerbes M, Butt HL, Roberts TK, Klineberg IJ. Preliminary determination of a molecular basis to chronic fatigue syndrome. Biochemical and Molecular Medicine 1996;1-9.
130. Freed DLJ. Dietary lectins and disease. In: Food Allergy and Intolerance. Eds: Brostoff J, Challacombe SJ. 1987 Bailliere Tindall, East Sussex, England.
131. Cuatrecases P, Tell GPE. Insulin-like activity of coconcanavalin A and wheat agerm agglutinin-direct interactions with insulin receptors. Proc Natl Acad Sci USA 1973;70:485-9.
132. Erickson RH, Kim YS. Interaction of purified brush-border membrane amniopeptidase N and dipeptidase IV with lectin-Sepharose derivatives. Biochim Biophys Acta 1983;743:37-42.
133. Freed DLJ. Non-Allergic Effects of Food. In Brostoff J, Challacombe SJ (eds.): Food Allergy and Intolerance. London, Bailliere Tindall 1987,375-400.
134. Ganguly P, Fossett NG. Evidence for multiple mechanisms of interaction between wheat gern agglutinin and human platelets. Biochim Biophys Acta 1980;627:256-261.
135. Hedo JA, Harrison LC, Roth J. Binding of insulin receptors to lictins: evidence for common carbohydrate determinants on several membrane receptors. Biochemistry 1981;20:3385-3393.
136. Hilgert I, Horejsi VA, Angelisova P, Kristofova H. Lentil lectin effectively induces allotransplantation tolerance in mice. Nature 1980;284:273-5.
137. Livingston JN, Purvis BJ. Effects of wheat germ agglutinin on insulin binding and insulin sensitivity of fat cells. Am J Physiol 1980;238:E267-75.
138. Nirmul G, Severin C, Taub RN. In vivo effects of con A. I. Immunosuppressive effects. Transplantation 1972;14:91-5.
139. Oppenheim JJ, Rostenstreich DL, eds: Mitogens in immunology. New York: Academic Press, 1976.
140. Shier WT. Concanavalin A as in inflammogen. In: Bittiger H, Schnebli HP, eds. Concavalin A as a tool. London: John Wiley and Sons. 1976;573-9.
141. Stillmark H. Uber rizin, ein giftiges ferment aus Samen von Ricinis communis L., und ainigen anderen Euphorbiaceen. Dorpat (Tartu), 1888. Inaugural dissertation.
142. Landsteiner K, Raubitschek H. Boebachtungen uber Hamolyse and hamagglutination. Zenbralbl Bakteriol 1907;45:660-7.
143. Boyd WC. Lectins. Ann NY Acad Sci 1970;169:168-90.
144. Renkonen KO. Studies on hemagglutinins present in seeds of some representatives of family of leguminoseae. Ann Med Exp Biol Fenniae 1948;26:66-72
145. Boyd WC, Shapleigh E. Diagnosis of subgroups of blood groups A and B by use of plant agglutinins (lectins). J Lab Clin Med 1954;44:235-7.
146. Hedo JA, Harrison LC, Roth J. Binding of insulin receptors to lictins: evidence for common carbohydrate determinants on several membrane receptors. Biochemistry 1981;20:3385-3393.
147. Hilgert I, Horejsi VA, Angelisova P, Kristofova H. Lentil lectin effectively induces allotransplantation tolerance in mice. Nature 1980;284:273-5.
148. Livingston JN, Purvis BJ. Effects of wheat germ agglutinin on insulin binding and insulin sensitivity of fat cells. Am J Physiol 1980;238:E267-75.
149. Nirmul G, Severin C, Taub RN. In vivo effects of con A. I. Immunosuppressive effects. Transplantation 1972;14:91-5.
150. Oppenheim JJ, Rostenstreich DL, eds: Mitogens in immunology. New York: Academic Press, 1976.
151. Edwards JE, Jr. Invasive candida infections: Evolution of a fungal pathogen. N Eng J Med 1991;324:1060-1062.
152. Ali M, Ali O, Bradford R. et al Immunostaining of candida organisms in peripheral smears. (Abstract). 1995. American Academy of Otolaryngic Allergy, Spring Meeting, Palm Desert, CA.
153. Ali M and Ramanarayanan MP: A computerized micro-ELISA assay for allergen-specific IgE antibodies. Am J Clin Pathol 1984;81:591.
154. Ali M, Ramanarayanan MP, Nalebuff DJ, et al: Serum concentrations of allergen-specific IgG antibodies in inhalant allergy: Effect of specific Immunotherapy. Am J Clin Pathol. 1983;80:290.
155. Ali M. The bloodstream: An Open Ecosystem. In RDA: Rats, Drugs and Assumption. Page 424-435. 1995 Life Span, Denville, New Jersey.
156. Ali M. Naked bacteria, naked yeast. In RDA: Rats, Drugs and Assumptions. Pages 455-457. 1995 Life Span, Denville, New Jersey.
157. Walsh TJ et al. Detection of circulating Candida enolase by immunoassay i patients with cancer and invasive candidiasis. N Eng J Med 1991;324:1026.
158. Roberts GD. Detetction of fungi in clinical specimens by phase-contrast microscopy. J Clin Micrbiol 1975;2:261-265.
159. Taschdjian CL, et al. Post Mortem Studies of Systemic Candidiasis I. Diagnostic Validity of Precipitin Reaction and Probable Origin of Sensitization to Dytoplasmic Candidal Antigens. Sabouraudia 1969;7:110.
160. Jarvis WR. and the National Nosocomial Infections Surveillance System. Centers for Disease Control. Nosocomial Fungal Infections. January 1980-April 1990. Presented at the Third International Conference on Nosocomial Infections. Atlanta July 31-August 3, 1990.
161. Mattman LH. L forms isolated from infections, in Microbial Protoplasts, Spheroplasts, and L Forms. Guze L.B., Ed., Williams & Wilkins, Baltimore, 1968, 472-483.
162. Mattman LH, Tunstall LH, Kispert WG. A survey of L variation in the salmonellae, Zentralbl, Bakteriol, Parasitekd, Infektionskr, Hyg. Abt. 1 Orig. 1969;210:65-74.
163. Mattman LH, Tunstall LH, Rossmoore HW. Induction and characteristics of staphylococcal L forms. Can J Microbiol 1961;7:705-713.
164. Almquist E. Studien uber das Verhalten einiger pathogenen mikroorganismen bei niedriger temperatur. Zbl. Bakt. I Abt Orig. 1908;48:175-186.
165. Almquist E. Variation and life cycles of pathogenic bacteria. J Infect Dis 1922;31:483-493.
166. Metchnikoff E. Untersuchungen uber die intracellular verdauung berwirbellosen thieren. Arb Zoologischem Inst Univ Wien 1883;5:141
167. Svoboda A. Regeneration of yeast protoplasts in agar gels. Exp Cell Res 1966;44:640-642.
168. Svoboda A, Necas O. Mechanisms of regeneration of yeast protoplasts. VI. An experimental blocking of regeneration of protoplasts. Folia Biol (Prague) 1968;14:390-397.
169. Mattman LH. Cell Wall Deficient Forms: Stealth Pathogens. CRC Press, Boca Raton, Florida, 1993.
170 Mattman LH. Cell Wall Deficient Forms: Stealth Pathogens. CRC Press, Boca Raton, Florida, 1993.
171. Prasad I, Bradley SG. Cell wall defective variant of Nocardia rubra. J Gen Microbiol 1972;70:571-572.
172. Emmons CW, Binford CH, Utz JP, Kwon-Chung KJ. Medical mycology. Lea and Febiger, Philadelphia. 3rd edition. 1976;192-196.
173. Rippon JW. Medical Mycology: The pathogenic fungi and the pathogenic actinomycetes. W. B. Saunders Co., Philadelphia. 1974;191-195.
174. Klotz SA. A fibronectin receptor on Candida albicansmediates adherence of the fungus to extracellular matrix. J Infectious Dis 1991;163:604-6
175. Louria DB, Stiff DP, Bennett B. Disseminated moniliasis in the adult. Medicine (Baltimore) 1962;41:307-337.
176. Lehrer RI. Measurement of candidiacidal activity of specific leukocyte types in mixed cell populations. I. Normal, myeloperoxidase-deficient, and chronic granulomatous disease neutrophils. Infect Immun 1970;130:241-245.
177. Lehrer RI, Cline MJ. Leukocyte candidacidal activity and resistance to systemic candidiasis in patients with cancer. Cancer (Phila) 1971;27:1211-1217.
178. Ali M. Oxidant injury damages energy enzymes. The Canary and Chronic Fatigue. 1994. Life Span, Denville, New Jersey.
179. Thompsen AM. The oxidizing capacity of the earth's atmosphere: probable past and future changes. Science 1992;256:1157-1165.
180. Tytgat J, Hess P. Evidence for cooperative interactions in potassium channel gating. Nature 1992;359:420-423.
181. Ism LL, De Jongh KS, Patton DE, et al. Primary structure and functional expression of the B1 subunit of the rat brain sodium channel. Science 1992;256:839-842.
182. Caliguiri M, Murray C, Buchwald D, et al. Phenotypic and functional deficiency of natural killer cells in patients with CFID. J Immunol 1987;139:3306-3313.
183. Targan S, Stebbing N. In vitro interactions of purified cloned human interferons on NK cells: enhanced activation. J Immunol 1982;120:934-935.
184. Suhadolanik RJ, Reichenbach NL, Sobol RW, et al. Biochemical defects in 2-5A synthetase/RNAase pathway associated with chronic fatigue syndrome with encephalopathy. In: The clinical and scientific basis of myalgic enceplalomyeltitis/chronic fatigue syndrome. Byron Hyde, ed. Ottawa, Canada. The Nightingale Research Foundation. (Chapter 67) 1992;613-7.
185. Linde A, Anderson B, Svenson SB, et al. Serum levels of lymphokines and soluble cellular receptors in primary Epstein-Barr virus infection and in patients with chronic fatigue syndrome. The J Inf Dis 1992;165-994-1000.
186. Buchwald D, Cheney PR, Peterson DL, et al. A chronic illness characterized by fatigue, neurologic and immunologic disorders, and active human herpesvirus-6. Ann Int Medicine 1992;116:103-131.
187. Teresaki P. In: Chronic fatigue syndrome. Goldstein J, ed. Chronic Fatigue Syndrome Institute, Beverly Hills, CA, 1990.
188. Gupta S, Vayuvegula B. A comprehensive immunological analysis in chronic fatigue syndrome. Scan. J Immunol 1991;33:319-327.
189. Handbook of Toxicology Vol 1. Spector WS. ed. W.B. Saunders, Philadelphia, 1956. Pages 184-5.
190. El-Ebiary M, Torres A, Fabregas N, at al. Significance of the isolation of Candida species from respiratory samples in critically ill, non-neutropenic patients: an immediate postmortem histologic study. Am J Respir Crit Care Med. 1997;156:583-590.
191. Aubourg P. L'Ozone medical: Production, posologie, modes d'applications cliniques. Bull Med, Paris 1938;52:745-749.
192. Payr E. Uber Ozone Behandlung in der Chirurgie. Munch Med Wschr 1936;82:220-291.
193. Hydrogen peroxide farr
194. Vosmaer A. Ozone: Its manufacture, properties and uses. Van Nostrand Publisher, New York 1916.
195. Roy D, Wong PKY, Englebrecht RS, Chian SK. Mechanism of enteroviral inactivation by ozone. Appl Environ Microbiol 1981;41:718-723.
196. Bolton DC, Tarkington BK, Zee YC, Osebold JW. An in vitro system for studying the effects of ozone on mammalian cell cultures and viruses. Environ Res 1982a;27:466-475.
197. Sleigh J, Linter SPK. Hazards of hydrogen peroxide. British Med J 1985;291:1706.
198. Shenep JL, Stokes DC, Hughes WT. Lack of antibacterial activity after intravenous hydrogen peroxide infusion in experimental escherichia coli sepses. Infect Immun 1985;48:607-610.
199. Dockrell HM, Playfair JH. Killing of blood-state murine malaria parasites by hydrogen peroxide. Infect Immun 1983;39:456-459.
200. Weiss SJ, Young J, LoBuglio A, et al. Role of hydrogen peroxide in neutrophil-mediated destruction of cultured endothelial cells. J Clin Invest 1981;68:714-721.
201. Root RK, Metcalf J, Oshino N, et al. H2O2 release from human granulocytes during phagocytosis. J Clin Invest 1977;60:1266-1279.
202. Farr CH. Possible therapeutic value of intravenous hydrogen peroxide. Second International Symposium; Chelating Agents in Pharmacology, toxicology and Therapeutics 1987; Charles University, Pilsen, Czechoslovak (In press).
203. Farr CH. Physiological and biochemical responses to intravenous hydrogen peroxide in man. J ACAM 1987; (In Press).
204. Ali M. Star Wars Medicine. In: The Cortical Monkey and Healing. pp 101-160. Institute of Preventive Medicine, Denville, New Jersey 1990. Bloomfield, New Jersey
205. Ali M. Enegetic- Molecular Medicine. In: RDA: Rats, Drugs and Assumptions. pp 1995. Life Span, Denville, New Jersey.

Medical Ozone Therapy Oxygen Therapies
Medical ozone therapy oxygen therapies, natural alternative, detoxify, kill infectious disease bacteria mycoplasma virus organism.

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Oxygen therapies, many therapeutic uses, effective, beneficial effects every part of our bodies. Medical ozone therapy is recognized by most as the most powerful versatile therapy known in alternative health because it plays a vital role in maintaining our well-being.

Oxygen (o2), along with foods is the primary nutrient that cells use to generate energy for all its functions. This energy is produced through oxidation of the unhealthy cells.

Oxygen therapies or oxidative therapies and their therapeutic uses included here are autohemotherapy, auricular insufflation, colonics, Intra-muscular, Intra-arterial, ozonated olive oil, ozonated steam, ozonated water, rectal insufflation and hydrogen peroxide.

Therapeutic Use Oxygen Therapies
Using medical ozone therapy, it is extremely important that you receive all the positive effects and not become dissatisfied from its use. It will work for you, if you apply it properly. The success of this depends on retaining the mixture of gas and allowing it to absorb through the colon.

Those with large intestine that needs cleaning, you will be unable to retain the gas and have to release it after a short period of time. As treatment progress you should be able to retain it for longer periods.

Medical ozone therapy is introduced into the rectal cavity it is called rectal insufflation. It is important to receive all the optimum benefits that it can deliver. If the large intestine is lined with debris it will not absorb.

Gas has to absorb through the intestinal walls during rectal insufflation for it to absorb into the bloodstream; therefore, the o3 is then carried through the circulatory system when the large intestine is clean.

Some people are using this therapy in the rectum (rectal insufflation) or vagina for 30 seconds, one to three times per day for the first week. It is best to do this immediately following an enema, a colonic treatment, or soon after a bowel movement.

Tiny tube is introduced a little way into the desired cavity which introduces up to half a liter of pure ozone in a humidified gas. The gas then enters the bloodstream through the intestinal walls.

Process is painless and generally creates a sense of increased vitality and well being because the blood is being oxygenated and nourished.

Humidifier bottle is important when using medical ozone therapy in the vagina or rectum at concentration of 27 to 32 mcg/ml. Oxidizing the skin tissue may result without the added moisture. When the gas is humidified, it is more effectively absorbed into the tissue. Generators with lower production levels are safe without the humidifier. Concentration over 72 will inhibit healthy blood cells.

Turn the generator on and the gas flowing, a catheter is inserted anywhere from 2 to 3 inches. Apply vitamin E or K-Y Jelly to the catheter for lubrication when needed. The flow rate is set at 1/2 liter/minute, or 5 cc/min. Some prefer to reduce the flow rate to 1/32 liter/minute. This allows for higher levels and longer exposure times.

One can usually do a rectal insufflation applications for 10 minutes and a vaginal for 30 minutes at these low flow rates. The low flow method allows for a higher contact time, which increases the absorption of it throughout. It also saves on oxygen and helps prevent cramping.

Cases of high infection or candida, most start treatments with daily uses of 2 to 3 times for 30 days. Start with a 60 second approach, if you cannot hold it in, try the 30 seconds and work up to 60 seconds.

After 30 days most will revert to one a day if the large intestine is clean. For most, the fastest and most efficient way to loosen the encrusted debris is by irrigating the colon first.

Methods used for cleaning are called colonic, enemas, or high colonic irrigation. Colonics will help loosen the debris in the colon faster if ozone and hydrogen peroxide is used in the irrigation water.

Activated oxygen is oxidizing the bad bacteria, candida, yeast and so forth in the large intestine, excessive gases may be produced. Try not to pass the gas soon after because it is usually the gas that is leaving. In cases where you cannot retain the gas, make sure you are near or on the throne.

Slight heating sensation is felt as the activated oxygen is oxidizing the germs. Heat may be more noticeable in the vagina and the ear. The heating sensation is only temporary.

Some may experience a minor rash or itch on the skin as the system is dumping out the toxins and going through the cleansing effect. Some will increase with their oxidative therapies for faster elimination of the accumulated debris.

When you increase your detox, you also need to increase your vitamin-mineral (especially electrolytes) supplements and vitamin E. Eating fresh vegetables and drinking lots of water will help flush out the waste from the intestines at a faster rate.

Method for absorbing ozone through the skin is by injecting it into a suit below the neck. Plastic bag can be used for the arm, leg or foot and sealing it off tight with the tube inside.

Most will stay inside the suit for 30 minutes. Before getting in the bag or suit, it is best to take a warm shower and remain damp. This opens the pores and allows the gas to absorb at a much faster rate.

Some people use it in the ear for one minute each, three times a day, or three minutes in each ear, alternating every minute. This method is called auricular insufflation.

Some people with arthritis problems will fill a container with warm water, large enough for the foot or hand and let the activated oxygen bubble under the limb for about five minutes. The warm water opens the pores allowing it to penetrate. After the first or second application, itching may occur. You should experience movement without stiffness or pain soon after with minor arthritis problems.

Using ozonated steam in cabinets is currently being used around the world for alternative health by aesthetician, chiropractors, massage therapists, and other practitioners because they recognize this as a natural way to detoxify and cleanse. Ozonated steam stimulates circulation and increases the oxygen supply.

Ozonated olive oil has many therapeutic uses and benefits. Its used as a topical application for dry skin and used as a beauty aid for wrinkles, and for treatment of sunburn. It can be inhaled directly when bubbled through the olive oil. Ozonated olive oil works when applied for cuts, bruises and other conditions.

Another method of inhalation in low concentration is through room a air purifier. This method is the simplest for absorbing it into the lungs and circulatory system.

Lemon, orange and aloe vera juice can be ozonated for drinking or applications to the skin. By ozonating two cups of fresh lemon juice for six hours (use a larger container because of the bubbles) has been used on all skin conditions like skin cancer, dry skin, psoriasis and ulcers.

Other topical applications have been used on bruises, burns, fistula, decubitus, gangrene, infections, muscle pains, radiation damage, and used to promote the healing of wounds.

Some physicians are injecting ozone directly into cancer tumors or into the muscle (Intra-muscular) for treating infections. Injecting it into the blood through the portal vein (Intra-arterial) may cause some adverse effects in some people. Another method, which purifies the blood of bacteria and infectious disease causing mycoplasmas, is called autohemotherapy. About 50 to 100 ml. is withdrawn and mixed with medical ozone and then reintroduced by intravenous drip back into the patient.

Ozone is a natural alternative to purify water. Research shows drinking ozonated water helps allergies, carcinoma, cold sores, candidiasis, headaches, gastritis, gum disease, mouth ulcers, thrush, ulcers; increases circulation, reduces infections after dental work, helps remove free radicals, helps colds, flu and virus, cleans wounds and minor bruises.

Drinking ozonated water also increases the oxygen level throughout and accelerates the healing process. Hydrogen peroxide (H2O2) is a natural by-product of most ozone oxidizing processes. Hydrogen peroxide is another great natural alternative for your health.

There are three methods used for administering hydrogen peroxide to detoxify; orally, intravenous and through colonic. These applications are called Oxidative Therapies. Diseases that have benefited from this oxidative therapy are heart and cardiovascular, pulmonary, infectious and immune diseases; in addition, Cancer, Parkinson and Alzheimer.

Some prefer a 25-day program of oral treatments using 35 percent food grade hydrogen peroxide for cleansing. They usually start with 3 drops mixed in an 8-ounce glass of non chlorinated pure water, juice or milk and taken 3 times a day. Dosage is increased by 1 drop per day as they work up to 25 drops 3 times a day.

Essential to provide your bodies with the necessary supplements during any oxygen therapy. OXY-MEGA colon cleanser and liquid nutrients like Sea Power Plus will accelerate the efficiency of medical ozone therapy and stimulate the internal cleansing and healing process.

Old technology with a new beginning; especially, in alternative health medicine. Its a natural alternative that could bring new life to everyone.

Medical Ozone Therapy Legal?
Medical ozone therapy is recognized in Bulgaria, Cuba, Czech Republic, French, Germany, Israel, Italy, Mexico, Romania and Russia. It is currently used legally in 16 Nations. Eleven in the USA like AK, CO, GA, MN, NY, NC, OH, OK, OR, SC and WA have already passed access-type bills to ensure that alternative therapies are available to consumers. Physicians here can legally use it and other safe effective non-conventional treatments as an alternative treatment in their practice without being persecuted.

Efforts are also underway in CA, DE, FL, KY, NJ, MA, MO, VA and WY to pass similar legislation. The bill HR-1964/S1378 will provide greater access to our health freedoms allowed by our federal government.

Equipment necessary with inexpensive ozonator like the AOS-1M Medical Ozonator is available. Sensible low cost natural alternative to the more expensive types.

Unconventional Therapies - Hydrogen Peroxide
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(H2O2)
The role of your cancer health professional is to create an environment of openness and trust, and to help in making informed decisions about alternative/complementary therapies. Collaboration will improve the safe integration of all therapies during your experience with cancer. The "Summary" and "Professional Evaluation / Critique" sections of this Unconventional manual are cited directly from the medical literature, and are intended to help in the objective evaluation of alternative/complementary therapies.

Summary
" Patients with cancer should not consider oxygen therapies as either alternative (first-line) or adjunct (complementary) therapies." (Cassileth)

"After studying the literature and other available information, the American Cancer Society has found no evidence that treatment with hydrogen peroxide or other 'hyperoxygenating' compounds is safe or results in objective benefit in the treatment of cancer. Lacking such evidence, the American Cancer Society strongly urges individuals with cancer not to seek such treatment." (CA)

Description / Source / Components
" Hydrogen peroxide (H2O2) is composed of two atoms of oxygen and two atoms of hydrogen. It is formed when water reacts with a single atom of oxygen. ... Most hydrogen peroxide treatments involve injection of diluted solutions of hydrogen peroxide in doses given over a period of one to several weeks." (Cassileth)

"Hydrogen peroxide is unstable and decomposes violently when in direct contact with tough surfaces or traces of organic or particulate matter. Light, agitation, heating, or chemical substances like carbonates, proteins, chlorides, charcoal, and iron all accelerate the rate of hydrogen peroxide decomposition in solution. One volume of 30% hydrogen-peroxide solution will yield 100 volumes of oxygen gas when it decomposes." (Green)

Kurt Donsbach runs Hospital Santa Monica, which uses hydrogen peroxide on patients. "Clinic literature states that hydrogen peroxide is administered intravenously, orally, in ear drops, as a nasal spray, as a tooth gel, as breath drops, and via enemas." (Barrett)

"Some promoters claim that the 3%-H2O2 product available in pharmacies is contaminated, so they recommend either reagent-grade (30%) or the 35% variety most commonly sold in health food stores. Proponents refer to the 35% version as 'food-grade peroxide', although this is not a scientifically recognized term." (CA)

History
The claims of oxygenation promoters are based on the concepts of William F. Koch (1885-1962) and Otto Warburg (1883-1970). (Green)

"William F. Koch, a Detroit physician, theorized in 1919 that cancer was caused by a metabolic defect brought on by a single toxin produced by an injury or irritation. He proposed that toxins produced during metabolism and by bacteria were normally burned off during oxidation of carbohydrates. If the toxins persisted, they damaged the toxin-burning system and converted a normally present 'harmless germ' into a virulent cancer-causing one." (Green)

"A major theoretical foundation for oxygen therapy is the work of Otto Warburg, M.D., winner of the Nobel Prize for medicine in 1931 (for elucidating the chemistry of cell respiration). Warburg observed that cancer cells have lower respiration rates than normal cells. He postulated that cancer cells therefore grow better in a low-oxygen environment, and that introducing higher oxygen levels could retard their growth or kill them." (Cassileth)

"Recent efforts to popularize hydrogen peroxide as an 'alternative therapy' are due largely to the activity of Father Richard Wilhelm, a retired high school teacher and former Army chaplain . . . . Father Wilhelm claims to have discovered the healing potential of H2O2 through acquaintance with Edward Carl Rosenow, MD, a physician who headed the Mayo Clinic's division of experimental bacteriology from 1915 until 1944, when he retired. Dr. Rosenow's papers, however, contain no evidence that he promoted the internal use of hydrogen peroxide for the control of cancer, arthritis, or any other degenerative disease." (CA)

"Other active promoters of hydrogen peroxide therapy are Kurt Donsbach, PhD, Walter Grotz, George Borell, Ed McCabe, and Charles Farr, MD, PhD." (CA)

Proponent / Advocate Claims
" Hydrogen peroxide will split into a molecule of water (which consists of two hydrogen atoms plus an oxygen atom) and one atom of oxygen. This single oxygen atom, according to oxygen therapy advocates, provide oxygen that the body uses both to prevent diseases from starting and to fight diseases already present in the body." (Cassileth)

"They claim that toxins that adulterate processed foods, the environment, and medications damage the oxidative metabolism of normal cells which then regress into anaerobic metabolism in which an inferior energy is produced, resulting in cancer." (Green)

"Donsbach claims that injected peroxide will boost blood oxygen levels which, in turn, kill cancer cells." (Barrett)

Promoters believe that hydrogen peroxide "kills cancer cells by supplying more oxygen than they can tolerate." Some also claim that "soaking an affected body part in peroxide can cause tumors to separate from the body so that they can be 'wiped away' and that drinking H2O2 can reduce the size of throat tumors." (CA)

Professional Evaluation / Critique
" Hydrogen peroxide does participate in the bactericidal processes within activated phagocyte cells. But when it escapes from the cells into the adjacent extracellular space during the inflammatory process, it becomes a major contributor to the tissue damage seen in lung disease, malignancies, and hemolysis. The presence of pharmacological concentrations of hydrogen peroxide in the blood is clearly a double-edged sword which can easily cause as much harm as it can cause good." (Green)

"The amount of oxygen contained in the few cubic centimeters of peroxide included in Donsbach's 4-hour intravenous infusions is less than the amount in a single deep breath of air." (Barrett)

"Oral hydrogen peroxide would automatically be ineffective since all of the hydrogen peroxide would be eliminated in the stomach forming water and inert gaseous oxygen which would then be lost in burping or passing flatus. No effect would occur in the body." (Personal)

"In 1988, the U.S. Postal Service issued Donsbach a cease and desist order to stop him from claiming that the hydrogen peroxide used orally or intravenously is effective against cancer or arthritis, or that it is fit for human consumption." (U.S. Congress)

Hydrogen peroxide is a treatment provided by the Bio-Genesis Clinic in Mexico. However, "instead of presenting the public with sound, verifiable, scientific research and conclusions, clinics such as Bio-Genesis seem to rely more heavily on testimonials from former patients as their proof." (DuBois)

Toxicity / Risks
" Hydrogen peroxide can be harmful, causing toxic reactions if taken internally in excessive amounts or as an undiluted preparation." (Cassileth)

"A continuous infusion of peroxide that results in 0.01 volume per 100 ml blood can cause an arterial gas embolism [sudden blocking of an artery] and irreversible lung damage. That such adverse reactions do occur is clear from reports in the medical literature. These incidents include: oxygen gas emboli, necrosis [the sum of the morphological changes indicative of cell death], and gangrene following peroxide enemas or colonic lavage [washing out of the colon]; emphysema [accumulation of air in tissues or organs] following peroxide mouthwash or gargle; and ulcerative colitis [inflammation of the colon], gas embolism, and emphysema following deep wound irrigation. Peroxide ingestion results in respiratory arrest, seizures, gas embolism in the portal circulation, shock, and acute hemolysis [disruption of red blood cell membrane causing release of hemoglobin]. Stroke and multiple cerebral infarcts and venous embolism follow irrigation of anal fistula [one opening on the cutaneous surface of the anus] and irrigation of surgical wounds." (Green)

"H2O2 must be diluted sufficiently or it may cause chemical burns. H2O2 often cause nausea when taken orally." (Ontario)

"Thirty-five percent hydrogen peroxide is commercially available as an oxidant and disinfectant. This solution is currently sold and promoted in health food stores in th United States as a means of 'improving oxygenation' in people with coronary artery disease and other health problems. Our findings show the high toxicity of concentrated hydrogen peroxide. CNS [central nervous system] damage and death are likely consequences after ingestion of this agent." (Ashdown)

"Promoters of hydrogen peroxide tend to downplay its potential for harm . ... In fact, however, during the past three years, six children have been seriously poisoned and one died as a result of accidentally drinking the concentrated solution stored in their refrigerator. The product in the fatal case had been obtained by mail order as an alternative medicine. A near-fatal case of ingestion by an adult also has been reported." (CA)

"The present study clearly demonstrates that H2O2 acts as a carcinogen. Reactive oxygen intermediates have been reported to induce single-strand breaks in cellular DNA, oxidation of DNA bases, chromosomal aberrations, and DNA-protein cross-links." (Okamoto)

Costs
Dr. Paul V. Beals charges $75 US for each hydrogen peroxide IV treatment. (Fink, 1997)

References
Ashdown BC, et al. Hydrogen peroxide poisoning causing brain infarction: neuroimaging findings. American Journal of Roentgenology 1998;170:1653-5.

Barrett S, Cassileth BR, editors. Dubious cancer treatment. Tampa, Florida: American Cancer Society, Florida Division, 1991:60-61.

CA (Anonymous). Questionable methods of cancer management: hydrogen peroxide and other 'hyperoxygenation' therapies. CA: a Cancer Journal for Clinicians 1993;43:47-56.

Cassileth BR. Alternative medicine handbook: a complete reference guide to alternative and complementary therapies. New York: W.W. Norton & Co., 1998:194-96.

DuBois E. Distinctively dubious. Journal-Press, Buffalo, Mn. 1986 Sept. 18:4A.

Fink JM. Third opinion: an international directory to alternative therapy centers for the treatment and prevention of cancer and other degenerative diseases. 3rd ed. Garden City Park, New York: Avery Publishing Group Inc., 1997:36-37.

Green S. Oxygenation therapy: unproven treatments for cancer and AIDS. Sci Rev Alt Med 1998;2:6-12.

Okamoto M, et al. Transformation in vitro of a nontumorigenic rat urothelial cell line by hydrogen peroxide. Cancer Research 1996;56:4649-53.

Ontario Breast Cancer Information Exchange Project. Guide to unconventional cancer therapies. 1st ed. Toronto: Ontario Breast Cancer Information Exchange Project, 1994:242-247.

Personal communication to BC Cancer Agency Cancer Information Centre. (BCCA Cancer Information Centre search file 1121G)

U.S. Congress, Office of Technology Assessment. Unconventional cancer treatments. Washington, D.C.: U.S. Government Printing Office 1990 Sept:114.

Revised February 2000

Oxygen and Cancer
AlkalizeForHealth

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"The doctor of the future will give no medicine, but will interest his patients in the care of the human frame, in diet and in the cause and prevention of disease."
- Thomas Edison

"...we routinely see the blood of patients change color as they improve in their health." - Dr. Donsbach, page 66.

"We know about hydrogen peroxide, but, frankly speaking, we are a profit motivated company and there is no profit in hydrogen peroxide." - Major Drug Company, quoted in McCabe, page 56.

Hydrogen peroxide is water with extra oxygen attached. The formula for water is H2O, and for hydrogen peroxide is H2O2.

In the 1950's, Dr. Reginald Holeman gave cancerous mice hydrogen peroxide in their drinking water. In 60 days the tumors disappeared. - McCabe, page 11.

In the 1980's, Winifred Wirth repeated Dr. Holeman's experiment twice with the same results. - McCabe, page 11.

The response of a tumor to chemotherapy or radiation is directly related to the level of tumor hypoxia. More hypoxia corresponds with greater resistance to treatment as well as increased tendency to metastasize. Testing the level of tumor hypoxia prior to treatment allows dosage of drugs or radiation to be adjusted.

Mice who receive hydrogen peroxide in their drinking water grow much larger and live twice as long. - McCabe, page 34.

3% H2O2 can be added to pets' drinking water at the rate of 1 ounce per quart of non-chlorinated water. - Dr. David Williams.

"We know it is oxygen which does the work of normalizing the joints in arthritis." - Dr. Donsbach, page 37.

Dr. Edward C. Rosenow, author of 450 published medical papers and an associate at the Mayo Clinic for over 60 years...proved over 80 years ago (1914) that bacteria could be found consistently in the lymph nodes that drain joints. He was probably the first scientist to postulate that H2O2 would help arthritis because of its ability to supply oxygen to oxygen-hating organisms causing arthritis (streptococcus viridans). - Dr. Douglass, page 6.

Putrefactive bacteria that break down our body when we die thrive in the absence of oxygen.

Viruses are "anaerobic" creatures which thrive in the absence of oxygen.
- Dr. Kurt Donsbach

Yeast, mold and fungus live in an anaerobic environment.

Most strains of harmful bacteria (and cancer cells) are anaerobic and cannot survive in the presence of oxygen or H2O2. - Dr. David Williams

Oxygen is FREE. Obtain all you can by ALWAYS using the full capacity of your lungs when you breathe. Slow, deep breathing.

Hydrogen peroxide (H2O2) dissolves dental plaque, creates healthy gums, and whitens teeth. A combination of baking soda and hydrogen peroxide makes the best toothpaste.

Add to your bath water one pint to one quart of 3% hydrogen peroxide. It invigorates, relieves pain, and stimulates your mind. It reduces stiffness and soreness like no other treatment. We give all our patients a whirlpool bath with the equivalent of one gallon of the 3% in it every other day. - Dr. Donsbach, page 43.

"6 fluid ounces of the 35% food grade hydrogen peroxide is equivalent to 2 quarts of 3%..." - Dr. Donsbach, page 46.

"Use 6 fluid ounces of the 35% food grade hydrogen peroxide in a bathtub full of rather warm water. Be sure that the area you have problems with is fully immersed and soak for 20 minutes or more. I have seen joints that are stiff and sore relieved in just a few baths. Skin problems also respond to this form of use, including rashes, eczema, psoriasis, athletes foot, etc." - Dr. Donsbach, page 46.

" ...do not use more than 15 drops (of 35% H2O2) per enema bag of water." - Dr. Donsbach, page 47. (Editor's note: Healthy intestinal and vaginal bacteria are aerobic and will not be harmed by oxygen. In fact, they will appreciate it, whereas their anerobic competition will be destroyed.)

An effective douche or enema solution can be made using 3 tablespoons of three percent H2O2 in one quart of distilled water. - Dr. David Williams

"If you have a respiratory problem, use 12 ounces of the 3% hydrogen peroxide in one gallon of water in a cool mist vaporizer. It will be very beneficial in a wide variety of conditions such as emphysema, chronic obstructive pulmonary disease, bronchitis, pneumonia, etc." - Dr. Donsbach, page 49.

Robert Stroud, the Birdman of Alcatraz, healed birds with hydrogen peroxide and sodium perborate. Sodium perborate in water creates hydrogen peroxide. - McCabe, page 11.

Obesity is actually the biggest killer disease. Overweight people are twice as likely to contract a disease. Clean healthy bodies utilize food more efficiently and effectively. Highly oxygenated people require less food. - McCabe, page 87.

When the body lacks sufficient oxygen, then the body adapts. Foods and wastes are incompletely oxidized and a chain reaction towards ill health begins.

A few drops of 3% hydrogen peroxide in the ears may help remove ear infections.

Jehovah's Witnesses who refuse blood transfusions have been saved by hyperbaric oxygen chambers. Their limited blood supply became saturated with oxygen and the hypoxia (lack of oxygen) was removed.

12 drops of 35% hydrogen peroxide in a quart of milk may be an alternative to pasteurization.

"Ozone selectively inhibited the growth of human cancer cells." - Rao Sweet, et al, Science, 1980.

"The FDA won’t spend a dime on ozone research, but they spent over $1 million intimidating, harassing, and persecuting me alone." - Dr. Jonathan Wright

Researchers have found that, for some reason, the addition of copper to peroxide increases the lethality of peroxide on bacteria by 3,000-fold. - Dr. Douglass, page 63.

There is a definite correlation between mental clarity and more oxygen in the blood.

Hypoxemia or, as Olney called it, "blocked oxidation," followed by fermentation of sugar in cells, is the prime factor in malignant, viral, bacterial, and allergic diseases. - Dr. Douglass.

Being able to increase arterial oxygen levels following a stroke can dramatically influence the degree of brain damage. - Dr. David Williams Alternatives November 2001.

"My wife is quite faithful in tending her roses. She sprays them with a very dilute solution - 8 tablespoonfuls of 3% hydrogen peroxide in a gallon of water - and has the finest roses in the neighborhood. You should also spray the ground at the base of your plants. Spray the same solution on cut flowers and add a little to the water to make them last 50% longer." - Dr. Donsbach, page 49.

The friendly aerobic bacteria in your garden soil will be killed by the chlorine in chlorinated water. It is better to water your garden with oxygenated water.

President's Choice "Green" bleach sold by Loblaw's contains no chlorine. The active ingredient is hydrogen peroxide. The label describes the product as "color-safe, active oxygen bleach".

Chlorination of drinking water removes oxygen. Cooking and over-processing of our foods lowers their oxygen content.
- Dr. David Williams, Alternatives, June 1992.

Dr. Johanna Budwig of Germany has shown that for proper cellular utilization of oxygen to take place, our diets must contain adequate amounts of unsaturated fatty acids. - Dr. David Williams, Alternatives, June 1992. (Use flax oil in your salad dressing to get the omega-3 essential fatty acids recommended by Dr. Johanna Budwig)

The Alkalize For Health web site is updated regularly as new information comes along. Please bookmark this site now and come back from time to time. Thank-you for visiting.
The brighter red the color of your blood, the more oxygen it carries. The darker its color, the less oxygen it carries.

Arterial blood is generally a brighter red because it has recently passed through the lungs. Venous blood is generally a darker red because it has passed through the capillaries where the oxygen is transferred from the blood to the tissues.

"All normal cells have an absolute requirement for oxygen, but cancer cells can live without oxygen - a rule without exception." - Dr. Otto Warburg, quoted in Philpott, page 74.

Deprive a cell 60% of its oxygen and it will turn cancerous. - McCabe, page 192. Deprive a cell 35% of its oxygen for 48 hours and it may become cancerous. - Dr. Otto Warburg. Read Dr. Warburg's papers in the Library: Lecture 1, Lecture 2.

When the oxygen saturation of blood falls, conditions become ripe for the creation of cancer. Oxygen is removed from the arterial blood as it passes through the capillary system. If arterial blood is deficient in oxygen or if the blood flow is restricted by blocked arteries, then tissues oxygenated by the latter stages of the capillary system may be so deprived of oxygen as to become cancerous.

The oxygen transport system from the lungs to the cells can be interrupted at numerous points, and so there are many opportunities to deny oxygen to cells. Also, there are many ways that cells and their mitochondria can be directly damaged, thereby reducing the cells' ability to utilize the oxygen that is available.

Normal Metabolism vs. Cancer Metabolism

"The fuel on which the body's cells run is called adenosine triphosphate (ATP). ATP must be created by all cells, including cancer cells, for energy. The biochemical process in which ATP is created is called oxidation phosphorylation and is oxygen-dependent. Healthy cells require the conditions of alkalinity and high molecular oxygen (O2) to produce ATP and function properly. In contrast, non-oxygen-respiratory organisms - like cancer cells - make ATP by fermentation phosphorylation, which requires the conditions of acidity and low oxygen to function, and actually produces additional acids." - Philpott, page 75.

Cellular Respiration

The human body's main fuel is a simple sugar called glucose. Glucose comes from the plants we eat. Through photosynthesis, plants use light energy to produce glucose and oxygen from carbon dioxide and water.
Carbon dioxide + water + energy --> glucose + oxygen

Plants then use the glucose to create cellulose and complex carbohydrates. When we eat the plants, the complex carbohydrates are broken down by our digestive system into glucose. Then this food energy is converted to chemical energy by a series of reactions known as cellular respiration. Aerobic respiration uses oxygen.
Glucose + oxygen --> carbon dioxide + water + energy
This reaction occurs in mitochondria in cells. Aerobic respiration extracts the maximum amount of energy from glucose, because the molecule is completely broken down.

When the supply of oxygen is insufficient, there is a back-up system known as anaerobic respiration, that can release energy without oxygen.
Glucose --> lactic acid + energy
This reaction occurs in the cytoplasm of the cell. It does not put any extra pressure on the respiratory or circulatory systems, because it does not produce carbon dioxide, but it can cause muscle stiffness after exercise. Cancer cells have either wholly or partially switched to anaerobic respiration. Enzymatic decomposition of glucose in the absence of oxygen is also known as "fermentation", though in humans the end result is the production of lactic acid, not alcohol, because we lack the enzymes to produce alcohol.

"The ideal task of cancer therapy is to restore the function of the oxidizing systems in the entire organism." - Dr. Max Gerson, page 7.

Aerobic cellular respiration creates as many as 36 ATP molecules from each glucose molecule, and anaerobic respiration creates only 2 ATP molecules. Anaerobic respiration releases one eighteenth of the available energy. Cancer cells must feel very tired!

For more information regarding cellular respiration, see Hydrazine Sulphate and cancer and oxygen. Also, you can do a search of the Internet for subjects such as cellular respiration, cellular biology and ATP, fermentation, lactic acid fermentation, cellular metabolism and fermentation, adenosine triphosphate, healthy mitochondria, Dr. Otto Warburg, etc. Use your favorite search engine or the powerful Meta Search engine on our "Useful Links" page.


Causes of Cellular Damage

There are many things that can damage a cell and its mitochondria. These include oxygen deprivation, nutritional imbalances, physical trauma, toxic chemicals, allergic reactions, radiation, infections, parasites, and more. If the injury harms the mitochondria, thereby interfering with the production of ATP, then this can cause significant damage to the cell because ATP is needed for important cellular processes such as membrane transport, lipogenesis and protein synthesis. With damaged mitochondria, for its very survival the cell has no choice but to revert to the more primitive system of anaerobic respiration that is characteristic of cancer cells. Sometimes the damage is reversible, in which case the cell can be healed. Sometimes the damage is irreversible, and a way must be found to destroy the cell. Also, the causes of harm to the cells must be removed to prevent repeated damage or damage to additional cells. For more information, do an Internet search for mitochondrial damage, tissue injury, etc.

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Nutrients for Healthy Mitochondria

Oxygen is necessary for cellular respiration and energy production, but it must be carefully handled within the cell or the mitochondria will be damaged. Five nutrients necessary to restore and maintain healthy mitochondria are:

L-carnitine - for the proper oxidation of fats within cells
Coenzyme Q10 - is necessary for the synthesis of ATP, and prevents free radical damage within the cell
Alpha lipoic acid - helps regenerate vitamins E and C after they are oxidized
Vitamin E - protects cell membranes from free radical damage. Non-Synthetic Vitamin E
Vitamin C - inhibits the oxidation of cholesterol and supports production of the antioxidant glutathione.
Dr. Stephen Sinatra frequently writes about these nutrients in his newsletter. These nutrients should be available in your local health food store. His website is www.DrSinatra.com.

***

Vitamin C is needed for the synthesis of carnitine, which is required for long-chain fatty acids to enter mitochondria where they are used for energy production. - Annals of Internal Medicine 114:909-910, 1991. Most cancer patients are deficient in vitamin C.

The conversion of vitamin C into carnitine takes place in the liver. If you have cancer, your liver is probably not functioning properly. There are things you can do to restore liver health.

Read more about healthy mitochondria.

***

Cellular Metabolism is Controlled by Thyroid Hormones

The rate of cellular metabolism and energy production is regulated by thyroid hormones. These hormones are deficient in many people because their body has insufficient iodine to produce them. The result is fatigue, depression, overweight, dry skin, cold hands or feet, hair loss, brittle nails, puffy eyes, constipation, brain damage and a lower IQ. There is a simple way to correct iodine deficiency that you can read about here.

However, even if you have enough iodine, you may still have insufficient thyroid hormones due to the presence of iodine blockers in your diet. Chlorine and fluoride are iodine blockers commonly added to municipal drinking water. These chemicals compete with the uptake of iodine and slow the production of essential thyroid hormones. Certain foods have the same effect, such as soy products that can interfere with the absorption and assimilation of iodine. For healthy cellular metabolism, you need a healthy thyroid gland producing abundant thyroid hormones.

Also, a diet high in nucleotides will increase cellular metabolism and the production of energy. Essential fatty acids (omega-3 and omega-6 in equal quantities) increase oxidation, energy levels, and stamina. There are other suggestions in our discussion of physical exercise.

Oxygen vs. Cancer

"I have been so impressed with the results of the use of hydrogen peroxide that every cancer patient receives infusions of the 35% food grade hydrogen peroxide / DMSO mixture throughout their entire stay...it should be apparent where I rank hydrogen peroxide, since this is the only substance I use in EVERY cancer patient." - Dr. Donsbach, pages 39-40.

We have now administered over 30,000 infusions of hydrogen peroxide without a problem. - Dr. Donsbach, page 32.

"Tumor cells, bacteria, and other unwanted foreign elements in the blood can usually be destroyed with hydrogen peroxide treatment. Peroxide has a definite destructive effect on tumors, and, in fact, cancer therapy may prove to be the most dramatic and useful place for peroxide therapy." - Dr. Douglass, page 4.

"The Baylor team reasoned that if they put oxygen into the tumor mass by injecting H2O2 into the tumor, the tumor would be much more receptive to X-ray destruction. They studied a total of 190 patients using hydrogen peroxide infused into the artery leading to the tumorous cancer. The experiment took six years. Their results were astounding." - Dr. Douglass, pages 30-31.

"Peroxide may be the greatest breakthrough we've ever had for brain tumors. Surgery destroys brain tissue, and chemotherapy for brain neoplasms is just plain quackery." - Dr. Douglass, page 63.

"Both therapies (hydrogen peroxide and photoluminescence) should be given for maximum results in treating cancer." - Dr. Douglass, page 80.

Hydrogen peroxide is water with extra oxygen attached. The formula for water is H2O, and for hydrogen peroxide is H2O2. Another name for hydrogen peroxide would be hydrogen dioxide.

Lack of oxygen and high levels of acidity go together. One reason for this: "In the electron transport scheme during oxidative metabolism, electrons are transferred along a set of electron acceptors, ending up, ultimately with the combination of hydrogen and oxygen to form water. However, when there is an oxygen deficiency, the loss of electrons can result in the accumulation of positive hydrogen ions, which lead to blood acidification." - Sandra Goodman, PhD, Germanium - The Health and Life Enhancer, Chapter 4. You can read her book on the Internet here: http://www.positivehealth.com/permit/Articles/Nutrition/Germanium/chapter4.htm

People with various degenerative diseases are sometimes found to have low venous oxygen saturation. With proper care, the venous oxygen saturation level rises and their health & vitality improve dramatically.

Arterial oxygen saturation should be very high. "High O2 tensions were lethal to cancer tissue, 95% being very toxic, whereas in general, normal tissue were not harmed by high oxygen tensions. Indeed, some tissues were found to require high O2 tensions...", J.B. Kizer, quoted in McCabe, page 82. An "Oximeter" device to measure your blood oxygen level is available from www.rgarden.com for $380.

Daily Humming is Good For You

During humming, the gas exchange between the nasal passages and the sinuses is 98 percent, almost a complete exchange. During normal exhalation, without humming, the gas exchange rate is only 4 percent.

Poor gas exchange and poor circulation in the sinus cavities create a good environment for bacterial growth. Researchers suggest that daily humming could help reduce the incidence of sinusitis and upper respiratory infections.

Also, sinuses are major producers of nitric oxide, which helps dilate capillaries and increase blood flow. When nitric oxide levels are measured during humming, researchers find that they are 15 times higher than during normal breathing.

- Am J Respir Crit Care Med 02;166(2):131-2

Increasing the oxygen saturation of the blood and tissues can be approached from a number of different directions simultaneously:

1. Fresh air. Increase the amount of oxygen in the air you breathe by allowing fresh air into every room of your home, office and transportation. Open the windows. Install a Heat Recovery Ventilation System (HRVS) or Energy Recovery Ventilation System. By connecting the HRVS into your furnace ducts, you can provide temperature moderated fresh air to the entire home economically in every season.

2. Breathe deeply. Improper breathing causes oxygen deficiency. Use the full capacity of your lungs by expanding both the chest and lower abdomen. Pause for a few seconds between each inhalation and exhalation. Practice deep breathing for a few minutes every day. If you feel depressed, try breathing more deeply (Other suggestions for fighting depression may be found on our Sunlight page.). Learn Pranayama (comfortable breathing exercise) and practice for a few minutes before meditating.

3. Aerobic exercise increases the capacity of the heart to pump blood and increases the capacity of the lungs.

4. Eat smaller nutrient-dense meals (no empty-calorie junk food). Overeating causes oxygen deficiency. Do you feel tired after a big meal? Vitamin F increases the oxygen carrying capacity of the hemoglobin (red blood cells). Eat fresh foods and avoid decomposing (rotten) foods. Eat an alkaline diet and create an alkaline condition in the body.

5. Follow Dr. Dean Ornish's 4 step program to clean out your arteries (low fat vegetarian diet, exercise, non-smoking, meditation). Clean arteries will maximize the amount of oxygen-rich blood reaching the tissues.

6. Antioxidants help the body use oxygen more efficiently. Antioxidants include MAK, Alkaline Water, Microhydrin, Raja's Cup coffee substitute, Superoxide Dismutase (SOD) which is found in the greenest plants, co-enzyme Q10, organic germanium (a trace mineral), thioctic acid, taheebo/pau d'arco, vitamin C, Non-Synthetic Vitamin E, vitamin A, retin-A (a form of vitamin A), ginseng. Wheat germ is a good source of vitamin E. Oxy-Powder contains organic germanium as one of its ingredients.

7. Avoid carbon monoxide (vehicle exhaust, fumes from gas stoves & heaters) that reduces the oxygen carrying capacity of the blood. Fluoride also interferes with oxygen uptake (Donsbach, page 30). Alcohol and drugs rob the body of oxygen because the body must oxidize these substances during the process of their removal (McCabe, pages 86-87).

8. Consume supplementary oxygen from other sources such as oxygenated drinking water, fresh foods and juices, magnesium oxide, magnesium dioxide, magnesium peroxide, magnesium hydroxide ("milk of magnesia"). "We also know that when H2O2 is taken into the body (orally or intravenously) the oxygen content of the blood and body tissues increases dramatically." - Dr. David Williams.

9. Bathe in oxygenated water. Add one pint to one quart of 3% hydrogen peroxide to your bath water and soak in it. Be sure your bath water is free of chlorine (chlorine causes cancer). You can remove the chlorine by putting a filter on the shower head and fill the tub via the shower.

10. Practice EWOT therapy. Exercise With Oxygen Therapy (EWOT) is doing light exercise, such as on a treadmill or stationary bicycle, while breathing pure oxygen. EWOT produces the benefits of intravenous hydrogen peroxide therapy and you can do it at home. Set the O2 flow at 6 liters per minute, hook the little tube to your nose, and exercise at a moderate pace for 15 minutes while breathing pure oxygen. As part of your cancer prevention and health maintenance program, you can do this once a month. If you are ill with any disease, do EWOT more frequently. In particular, do EWOT after operations, chemotherapy, radiation treatment, x-rays, and burns. - Dr. William Campbell Douglass.

Bottled oxygen is generally a prescription item. However, you can purchase for home use an "oxygen concentrator" such as is used in "oxygen bars". Do an Internet search for suppliers of this device.

11. Practice hyperthermia. Hyperthermia increases circulation and removes toxins from the body via excessive sweating. One way carcinogens cause cancer is by attaching to cell membranes, thereby suffocating the cell even when adequate oxygen is otherwise available.

12. Intravenous hydrogen peroxide is inexpensive, safe and easy to administer (Altman, page 2). For an oxygen therapy international doctor and clinic list see www.oxytherapy.com. Also, with the help of a physician, you might try UBI (ultraviolet blood irradiation) therapy, which can produce a 50% increase in venous oxygenation within 10 minutes. This oxygenation is in the blood plasma, as there is no change in the number of red cells. - Dr. William Campbell Douglass (See Dr. Douglass's books in the recommended reading list below).

Using Diluted 35% Food Grade Hydrogen Peroxide Internally

Mix a few drops of 35% H2O2 into a glass of water. Take on an empty stomach (the oxygen will react with the food in the stomach), one hour before a meal or at least 3 hours after a meal.

Start with one drop of hydrogen peroxide 3 times per day. On the second day, increase to two drops 3 times per day. On the third day, increase to three drops three times per day. Increase in this manner each day until you reach 25 drops 3 times per day or the limit of your comfort. If your stomach gets upset at any level, go back one level. Hydrogen peroxide has an obnoxious taste and few people reach 25 drops.

When free of your health complaints, taper off by reducing your daily dosage. A good maintenance dose is a total of 1 - 2 drops per day.

- Dr. Donsbach, pages 44-45.

Editor's note: With hydrogen peroxide, more is not necessarily better. Moderation is the key.

***

Using Magnesium Peroxide Internally

For oral ingestion, however, I now believe the product of choice to be magnesium peroxide, and it may have even more to offer. The oxygen content is more stable than that in hydrogen peroxide and when it is chemically reduced, it leaves a very beneficial mineral, magnesium, as oxygen is released.

Comparison
% Oxygen Waste Product Taste Stability
H2O2 94% Water Metallic Fair
MgO2 57% Magnesium Pleasant Good


I choose to use hydrogen peroxide for infusion purposes and external use and a combination of hydrogen peroxide and magnesium peroxide for oral ingestion.
- Dr. Donsbach, pages 3-8.

Editor's note: For more information, do an Internet search for hydrogen peroxide and magnesium peroxide(MgO2). You also might want to consider magnesium hydroxide Mg(OH)2 commonly known as "milk of magnesia". Magnesium hydroxide is made by adding magnesium oxides to water. Evaporating the water reverses the process with the result being the white powder of magnesium oxides, suggesting that milk of magnesia might be an economical and readily available source of the magnesium peroxide that Dr. Donsbach recommends. There is also an excellent product called "Oxy-Powder" that you might want to read about.

magnesium oxide(s) + water --> magnesium hydroxide
magnesium hydroxide --> magnesium oxide(s) + water

***

Individuals who have had transplants should not undertake an H2O2 program. H2O2 stimulates the immune system and could possibly cause a rejection of the organ. - Dr. David Williams.

***

You should also be aware that there are now numerous hydrogen peroxide products on the market. Some are simply peroxide that has been flavored and mixed with sea minerals, aloe vera, inner tree bark or other ingredients to make the peroxide more palatable (Superoxy, Oxy Toddy, etc.) Other claim to have developed products that deliver more oxygen than does simple hydrogen peroxide (Aerox, Anti-Oxid-10, Di-Oxychloride, Aerobic 07, Aqua Pure, etc.). Basically you'll end up paying a small fortune and at best achieving the same results you can get for pennies by using hydrogen peroxide. - Dr. David Williams.

Oxygen vs. Disease

Hydrogen peroxide "has a stimulatory and regulatory effect on the immune system and may either directly or indirectly kill viruses, bacteria, parasites, yeast, fungi, and a variety of other harmful organisms. Our studies demonstrate a positive metabolic effect of an intravenous infusion of hydrogen peroxide." - Charles H. Farr, M.D., PhD. in Altman, page XI.

"Peroxide is certainly a universal agent which can almost always be tried for an illness, often with great success." - Dr. Douglass, page 154.

"The use of (intravenous) hydrogen peroxide was reported in 1920 during the influenza epidemic. Although excellent response was noted, there was no follow-up...I started primarily because I felt this was the perfect answer for Systemic Candidiasis, a condition which has resisted the best drugs and diets ever devised...All viruses are inhibited by a high oxygen environment." - Dr. Donsbach, pages 31, 42.

"We're just beginning to learn exactly how H2O2 works. It has been reported to work as far back as 1920. The English medical journal Lancet then reported that intravenous infusion was used successfully to treat pneumonia in the epidemic following World War I. In the 1940's, Father Richard Willhelm, the pioneer in promoting peroxide use, reported on the compound being used extensively to treat everything from bacterial-related mental illness, to skin disease and polio. [Father Willhelm is the founder of "Educational Concern for Hydrogen Peroxide" (ECHO), an non-profit organization dedicated to educating the public on the safe use and therapeutic benefits of hydrogen peroxide.]" - Dr. David Williams.

"Oxygen will destroy malaria." - McCabe, page 18.

In 1920, intravenous hydrogen peroxide cut the death rate from pneumonia in half. - McCabe, page 41.

Intravenous hydrogen peroxide is helpful with pulmonary disease, gangrene, arterioslerosis, aids, flu, asthma. - McCabe, page 44-46.

"One ounce of 35% hydrogen peroxide (per gallon of water) in a vaporizer every night in an emphysemic's bedroom, and they will breathe freer than they have breathed in years! I do this for my lung cancer patients." - Donsbach quoted in McCabe, page 59. (While most conditions respond remarkably to oral ingestion, emphysema is one condition in which intravenous infusion can be a godsend. - Dr. David Williams, Alternatives, June 1992.) Contact International Bio-Oxidative Medicine Foundation to find a doctor in your area who can provide this procedure.

"Put four ounces of 35% peroxide in a gallon of water. Run a cold humidifier in your bedroom all night with this mixture." - Dr. Douglass, page 64.

Gargle with 3% hydrogen peroxide for a sore throat. - McCabe, page 55.

"For mouth freshness in the morning, rinse with three percent hydrogen peroxide." - Dr. Douglass, page 58.

For many uses, the hydrogen peroxide is diluted to 1 1/2% or even 3/4% or less. - McCabe, page 57.

Hydrogen peroxide nasal mist cleans pockets of infection from the sinuses. "Take the drugstore variety, which is three percent; dilute it 50 percent with water and put five to ten drops in each nostril - sniff it up vigorously (it will burn a little). Do this twice daily and see if it helps. If it doesn't, then your problem is not your sinuses." - Dr. Douglass, page 61.

3% H2O2 can be used full strength as a foot bath for athlete's foot. Diabetics have found relief from circulation problems by soaking their feet in 1 pint of 3% peroxide mixed with 1 gallon of warm, non-chlorinated water for 30 minutes nightly. - Dr. David Williams.

Hydrogen peroxide has been used in the treatment of heart and blood vessel diseases (including arrhythmias, stoppage, heart disease, stroke and memory loss, angina, gangrene, inflammation, vascular and cluster headaches), pulmonary diseases (asthma, bronchitis, emphysema, pneumonia), infectious diseases (acute and chronic viral infections, bacterial infections, chronic fatigue syndrome, herpes, shingles, influenza, parasitic infections, candida), immune disorders (adult onset diabetes, multiple sclerosis, arthritis, hypersensitivity reactions), and other diseases (Alzheimer's, cancers, chronic pain, migraine headaches, Parkinson's disease). - Altman, page 18 - 19. Editor's note: Some cancers may be caused by infections, including fungal infection. Oxygen is a treatment for fungal infection.

The following is only a partial listing of conditions in which H2O2 therapy has been used successfully (Dr. David Williams, Alternatives, June 1992):Allergies Altitude Sickness Alzheimer's
Anemia Arrhythmia Asthma
Bacterial Infections Bronchitis Cancer
Candida Cardiovascular Disease Cerebral Vascular Disease
Chronic Pain Diabetes Type II Diabetic Gangrene
Diabetic Retinopathy Digestion Problems Epstein-Barr Infection
Emphysema Food Allergies Fungal Infections
Gingivitis Headaches Herpes Simplex
Herpes Zoster HIV Infection Influenza
Insect Bites Liver Cirrhosis Lupus Erythematosis
Multiple Sclerosis Parasitic Infections Parkinsonism
Periodontal Disease Prostatitis Rheumatoid Arthritis
Shingles Sinusitis Sore Throat
Ulcers Viral Infections Warts
Yeast Infections


Complementary nutrients to take with hydrogen peroxide and help increase oxygenation in the body include coenzyme Q10, organic germanium, niacin, vitamin E, flax oil, lecithin and acidophilus.

High levels of hydrogen peroxide are found naturally in breast milk and colostrum. One of its main functions is to activate and stimulate the immune system. Dr. Charles Farr has shown that hydrogen peroxide stimulates enzyme systems throughout the body. (Proceedings of the International Conference on Bio-Oxidative Medicine 1989, 1990, 1991.)

Vitamin C helps fight infections by producing hydrogen peroxide. Lactobacilli found in the colon and vagina produce hydrogen peroxide. This destroys harmful bacteria and viruses, preventing colon disease, vaginitis, bladder infections and a host of other common ailments. (Infect Dis News Aug.8, 91:5.)

"Hydrogen peroxide is one of the few simple miracle substances still available to the public. Its safety and multiple uses ranks it right up there with DMSO. If you've never used either of these compounds you're overlooking two of the most powerful healing tools ever discovered." - Dr. David Williams.

The 3% hydrogen peroxide (H2O2) available in grocery stores and drug stores contains stabilizers (such as phenol, acetanilide, sodium stanate and Tetrasodium phosphate). This hydrogen peroxide is for external use only, not for internal consumption. It is OK for brushing the teeth, gargling and as a mouth wash, providing you rinse your mouth after.

The 35% food grade hydrogen peroxide is for internal consumption and can be diluted for intravenous application. See oxygen therapy international doctor and clinic list - www.oxytherapy.com.

Other grades of hydrogen peroxide include 6% used by beauticians and contains bleach, 30-32% electronic grade used for washing electronic parts, 35% technical grade which contains a small amount of phosphorous, and 90% used as a source of oxygen in rocket fuel.

Hydrogen Peroxide and Ozone in Nature

The earth's atmosphere is surrounded by the "ozone layer". Ozone (O3) is created when radiation from outer space interacts with oxygen in the atmosphere.

O3 is heavier than O2 and tends to fall toward the earth. As it enters lower levels of the atmosphere it encounters water vapor and forms hydrogen peroxide (H2O2). Rain water contains a small percentage of hydrogen peroxide and this acts as a natural disinfectant in rivers and lakes. All living things are adapted to take in a small quantity of hydrogen peroxide in their diet, and even produce hydrogen peroxide as part of their immune functioning. However, it requires energy for the body to create hydrogen peroxide and so a sick person may be deficient.

Hydrogen peroxide in water is very stable and as the rain water flows into the ocean the hydrogen peroxide ends up in the ocean. As water evaporates, hydrogen peroxide evaporates and will survive steam distillation. In this manner, hydrogen peroxide travels around the natural hydrological cycle, acting as a natural disinfectant in the ecosphere. However, with increased pollution, the levels of of oxygen and hydrogen peroxide in the air and rainwater are decreasing.

Clean Drinking Water

30 parts per million is the concentration of hydrogen peroxide used to sanitize drinking water. Peroxide application is best accomplished by a metering device that keeps the application constant and thorough. - Dr. Donsbach, pages 53- 54.

Hydrogen peroxide and ultraviolet light are a simple and effective combination for drinking water sanitation. A combination of ozone and ultraviolet light is also effective, though more complex. As an added benefit, these methods of purifying drinking water will kill parasites such as cryptosporidium that are not destroyed by chlorine. Some cities in Europe have been purifying their drinking water with ozone since 1901.

"Ultraviolet light has been used in disinfection for many years and is, in fact, still used for that purpose. Any contaminated object, whether it be surgical instruments, bedding, room air, the human skin, or bodily fluids such as blood, can be cleansed rapidly of viruses and bacteria." Dr. William Campbell Douglass, page 11.

The use of ultraviolet light to disinfect air could be used to good advantage in day care centers, school classrooms, hospice dormatories and other situations where people are sharing the same air. The spread of antibiotic resistant respiratory infections such as tuberculosis could be reduced by this technology.

***

Dr. Douglass notes that UV light can disinfect air. This technology could easily purify air recirculating in airline cabins, helping to prevent the rapid global spread of airborne infections. The present situation is highly irresponsible.

According to Dr. David Williams, airlines are "traveling disease factories". A survey found up to 41% of the passengers carrying some kind of respiratory infection and some people were found to be traveling with temperatures of 100 degrees F or more. "Airlines are the perfect incubators for the replication and spread of pathogens", writes Dr. Williams, due to the constant recycling of air in the passenger cabin. "It's easy to see how one passenger with a respiratory infection could infect an entire planeload of passengers."

"Crashes and terrorists continue to frighten many people away from flying, but the hidden health risks associated with air travel should be more of a concern." - Dr. David Williams

Swimming Pools

"The therapeutic pool at Hospital Santa Monica uses only hydrogen peroxide as a purifying agent. Our office has been inundated with calls from homeowners who want to use hydrogen peroxide in their swimming pools. It seems that many are now tired of the chlorine which is a known health hazard. The average pool will require about eight gallons to begin with, then adding from one-half to one gallon per week to maintain a 30 parts per million concentration. This can easily be measured by using test strips available from...

Lab Safety Supply
PO Box 1368
Janesville, WI 53437
(800) 356-0783
www.labsafety.com
Item #57790 Peroxide Strips 0 - 100 ppm
50 test strips for $12.95 + S & H

You will have sparkling clear water, there will be no growth on the sides of the pool and, more important, you will not have red eyes from the irritation of the heavy amounts of chlorine in the pool water nor will your body be absorbing this dangerous chemical when you swim in it. NOTE: It has been estimated that full body contact for twenty minutes with chlorine-saturated water will allow absorption equivalent to drinking two quarts of the same water."
- Dr. Donsbach, pages 48-49.

You can find other suppliers of peroxide test strips by doing an internet search for "peroxide strips ppm".

Farm Use

Adding 30 ppm hydrogen peroxide to drinking water on farms causes:

- chickens do not get avian flu
- egg production goes up
- chickens taste better
- soaking decontaminates salmonella from broiler carcasses
- turkeys weigh more on less feed
- turkeys have lower mortality rate
- hog meat is more lean and higher grade
- reduce or eliminate need for antibiotics
- increased milk production and butterfat content, decreased bacteria count
- less mastitis
- foliar spray for crops

Other uses on farms (at varying concentrations):
- udder wash
- pipeline, milk can, & bulk tank rinse
- converts crop residues into animal feed (soak crop residue in 1% solution for 16 hours to break down fiber so it can be assimilated)
- power wash for barns, spray on floors & walls and leave until foaming subsides, then rinse
- disinfect water on fish farms
- reduced fungal growth on fish
- fish packed in ice made from oxygenated water are better preserved
- produce sprayed with oxygenated water lasts longer

Hydrogen peroxide is just water and oxygen. It is harmless and will not show up on a chemical residue test. The same 30 ppm is used for all farm animals and results in increased oxygen levels in the blood and cells.
- Dr. Donsbach, page 66.

***

Increase crop yields by spraying them with diluted hydrogen peroxide. Use 5 to 16 ounces of 35% mixed with 20 gallons of water per acre. For houseplants use one ounce of 3% per quart of water or 16 drops of 35% solution per quart of water.
- Dr. David Williams

Caution

For bulk application in swimming pools, drinking water and farm usage, 35% food grade hydrogen peroxide is available from chemical suppliers in 30 gallon drums or larger drums. If mistaken for water and swallowed, the 35% hydrogen peroxide can cause intense vomiting. If the vomit is inhaled into the lungs, death can result.

Keep out of the eyes. It can cause blindness! Contact of 35% hydrogen peroxide with the skin can cause the skin to whiten and sting. Flush immediately with water to dilute and remove the hydrogen peroxide. - Dr. Donsbach, page 50- 51.

"Recent advances in ozone manufacture and technology have created a great interest on my part in using humidified ozone by rectal insufflation. The methodology allows repeated treatment during the day without invasive procedures such as required to give an intravenous infusion.
- Dr. Donsbach, page 66.

It is essential that ozone generators do not produce electrical arcing, which creates nitrogen oxides that are highly toxic. - McCabe, page 92.

"There are over 6,100 articles in the scientific literature dating from 1920 on the scientific applications of hydrogen peroxide. It seems inconceivable that the astounding medical cures reported in science journals over the past 75 years could have been ignored." - Dr. Douglass, page 19.

"Unlike expensive pharmaceuticals, surgery, and other advanced medical modalities, these simple therapies are not going to fill the pockets of physicians, drug companies, and hospitals. Since those interests - primarily through professional, trade, and political action organizations - influence the direction of health care policy in this country, future research in bio-oxidative therapies will probably not be initiated by them. The future of alternative therapies like ozone and hydrogen peroxide is in the hands of the health-care consumer." - Altman, page 9.

Fermentation and Cancer

The ideal task of cancer therapy is to restore the function of the oxidizing systems in the entire organism. This, of course, is difficult to accomplish. It involves the following: 1) detoxification of the whole body, 2) providing the essential mineral contents of the potassium group, 3) adding oxidizing enzymes continuously as long as they are not reactivated and built in the body...This will create a near normal condition of the oxidizing system in the body, to which malignant cells with the fermentation system cannot adapt. - Dr. Max Gerson, page 7.

***

Gaston Naessens invented an incredible microscope that allows living tissue to be seen at much higher levels of magnification (30,000X, compared to 1,800X with a classical microscope). His microscope uses light with a very short wavelength to illuminate the object, and then this light is converted to frequencies visible to the human eye.

Hidden within the blood plasma he found tiny bodies he named "somatids". These somatids are observed to change from one form to another in a regular cycle. In a healthy person the somatids have a three stage cycle. In an unhealthy person the somatids have a 16 stage cycle.

The critical impetus between stages three and four that starts the unhealthy cycle is fermentation. This fermentation is the result of sub-cellular trauma that can be produced in many ways including exposure to chemical pollution, radiation, accidents, shocks, depressed psychological states, etc.

The 13 unhealthy somatid stages include forms identical to bacteria, yeast (fungus), and fibrous material (what tumors are made of). Bacteria can come from the outside or be internally generated and are not necessarily the cause of disease. Rather the bacteria are the result of disease, and the disease actually exists on a more subtle level, on the level of the somatids and the biological imbalance that permits the unhealthy forms of somatids to thrive.

By studying the blood of healthy people and people with various diseases, Naessens found that he could predict diseases the healthy people were going to get based on the condition of their somatids.

In traumatized animals, the somatids become highly active and begin to destroy the bodies of their hosts.

Naessens has become famous for treating diseases by monitoring the somatids to determine the effectiveness of the treatment. He has successfully treated many thousands of cases of cancer, aids and other diseases.

Somatids are fundamentally electrical in nature. Their nuclei is positively charged and the membrane coating their exterior is negatively charged. "Somatids are actually tiny living condensers of energy, the smallest ever found."

***

Dr. Robert Beck, the inventor of several electro-medicine devices, tells how people using his devices visited a medical practitioner using the dark-field microscope invented by Gaston Naessens. The blood samples taken from the electro-medicine treated individuals were perfect. Furthermore, the blood cells were virtually immortal. When the microscope slides were sealed around the edges with vaseline so that the blood could not dry, the cells remained alive and healthy for many weeks. Ordinary red blood cells begin to decompose within four hours.

***

The optical microscope developed by Royal Raymond Rife in the 1920s and 1930s also magnified living tissue about 30,000X. With his microscope, Rife was able to directly observe tiny organisms much smaller than bacteria that he isolated from cancer tumors, and the effect of various frequencies of electromagnetism (light) on these organisms. In this manner he was able to find a frequency that killed them. Using only light, he was able to cure cancer and many other diseases. Cancer patients were exposed to light of a certain frequency for three minutes every three days. After three months, fourteen of sixteen terminal cancer patients were fully recovered. Other diseases that could be cured by this method included tuberculosis, typhoid, leprosy, and hoof-and-mouth disease.

The tiny cancer-causing organisms could be isolated from tumors, cultured, injected into healthy animals where new tumors would form, and then be isolated once again from the new tumors. When placed onto plant tissue, it developed into fungus. Under certain circumstances, the cancer-causing organisms would transform themselves into bacillus coli, a common intestinal bacteria. The ability of an organism to change from one shape or size to another is called pleomorphism.

***

In the 1950s, Dr. Florence B. Seibert, Professor Emeritus of Biochemistry, University of Pennsylvania was able to isolate pleomorphic bacteria from cancer tumors, and also from blood samples from patients with varying types of leukemia.

"One must always consider that most malignancies are accompanied by an immuno-deficiency...Therefore, we could be dealing with a microbe that finds such a host merely a suitable environment for habitation." - Dr. Lida H. Mattman

"It was the chemical constituents and chemical radicals of an organism which enacted upon the unbalanced cell metabolism of the human body to produce disease...We have in many instances produced all the symptoms of a disease chemically in experimental animals without the inoculation of any virus or bacteria into their tissues." - Royal Raymond Rife.

***

Candidiasis is caused by an overgrowth of a yeast-turned-fungus, and Chronic Fatigue Syndrome is associated with a virus (Epstein Barr Virus)...The fact is both Candidiasis and Chronic Fatigue Syndrome are very responsive to the use of hydrogen peroxide and thousands of individuals have had fantastic results using it.

I have been so impressed with the results of the use of hydrogen peroxide that every cancer patient receives infusions of the 35% food grade hydrogen peroxide / DMSO mixture throughout their entire stay...it should be apparent where I rank hydrogen peroxide, since this is the only substance I use in EVERY cancer patient." - Dr. Donsbach, pages 7, 39-40.

"Remember, where cells get enough oxygen, cancer will not, cannot occur." Dr. Otto Warburg, 1966

Recommended reading:

Do a search using our Meta Search Engine for hydrogen peroxide. There is a lot of information available on the Internet.

Altman, Nathaniel, Oxygen Healing Therapies, Healing Arts Press, Rochester, Vermont 1998.

Bird, Christopher, The Galileo of the Microscope - The life and trials of Gaston Naessens, Les Presses de l'Université de la Personne Inc., St. Lambert, Quebec, 1990.

Bragg, Paul, and Patricia Bragg, Super Power Breathing for Super Energy, High Health & Longevity, Health Science, Santa Barbara, California.

Donsbach, Kurt, Oxygen, Oxygen, Oxygen, 1994.

Douglass, William Campbell, Hydrogen Peroxide: Medical Miracle, January 1996.

Dyer, Dr. David S., Cellfood, Vital Cellular Nutrition for the New Millennium, Feedback Books, 2000. Available from the author at drdaviddyer@earthlink.net. If you want to try an "oxygen supplement" you might consider Cellfood, which also contains enzymes, trace minerals and deuterium. Deuterium is the isotope of hydrogen that makes heavy water "heavy". Deuterium has interesting health benefits for many people, according to testimonials in the book. Do an Internet search for "Cellfood".

Lynes, Barry, The Cancer Cure that Worked: 50 Years of Suppression, Marcus Books, June 1987. This is the story of the Rife microscope. The ability to cure disease with light has been suppressed by pharmaceutical companies and their stooges in the American Medical Association and FDA.

McCabe, Ed, O2xygen Therapies, Energy Publications, Morrisville, NY, 1988.

Page Summary

Oxygen is at the very center of the cancer problem. The metabolism of oxygen was a great evolutionary leap allowing the transition from vegetative life to much more active forms of life. However, the anaerobic vegetative metabolism still lies dormant within every cell in your body and can become manifest if your cells are deprived of oxygen for any reason.

Maintaining oxygen metabolism throughout your body requires that the entire oxygen system be maintained and function properly. This includes the quality of air you breathe, proper use of your lungs, the efficiency of your blood to transport oxygen, the alkaline condition of your lymph to transport oxygen from the blood to the cells, regular exercise to move the lymph, adequate nutrition at the cellular level so that the oxygen can be metabolized, and absence of toxins at the cellular level that can interfere with oxygen metabolism.


--------------------------------------------------------------------------------

Off to a Fast Start...The Importance of Fresh Juices plus other ways to Strengthen Your Immune System


You now understand the importance of more oxygen and more alkalinity. One of the key ways of increasing your alkalinity is drinking lots of freshly made fruit and vegetable juices. Some doctors recommend to cancer patients that they drink one 8 ounce glass of these juices each waking hour of the day. You could never eat the amount of good nutrition you will get from these juices. The juices are also incredibly important to strengthen your immune system. There is a direct connection between the strength of the immune system and cancer according to the American Cancer Society Cancer Book edited by Dr. Holleb that states "only when the immune system is incapable of destroying these malignant cells will cancer develop." So lets move on now to a discussion of Fresh Juices plus other ways to Strengthen Your Immune System.

Using Diluted 35% Food Grade Hydrogen Peroxide Internally

Mix a few drops of 35% H2O2 into a glass of water. Take on an empty stomach (the oxygen will react with the food in the stomach), one hour before a meal or at least 3 hours after a meal.

Start with one drop of hydrogen peroxide 3 times per day. On the second day, increase to two drops 3 times per day. On the third day, increase to three drops three times per day. Increase in this manner each day until you reach 25 drops 3 times per day or the limit of your comfort. If your stomach gets upset at any level, go back one level. Hydrogen peroxide has an obnoxious taste and few people reach 25 drops.

When free of your health complaints, taper off by reducing your daily dosage. A good maintenance dose is a total of 1 - 2 drops per day.

- Dr. Donsbach, pages 44-45.

Editor's note: With hydrogen peroxide, more is not necessarily better. Moderation is the key.

***

Using Magnesium Peroxide Internally

For oral ingestion, however, I now believe the product of choice to be magnesium peroxide, and it may have even more to offer. The oxygen content is more stable than that in hydrogen peroxide and when it is chemically reduced, it leaves a very beneficial mineral, magnesium, as oxygen is released.

Comparison

% Oxygen Waste Product Taste Stability
H2O2 94% Water Metallic Fair
MgO2 57% Magnesium Pleasant Good

I choose to use hydrogen peroxide for infusion purposes and external use and a combination of hydrogen peroxide and magnesium peroxide for oral ingestion.
- Dr. Donsbach, pages 3-8.

Editor's note: For more information, do an Internet search for hydrogen peroxide and magnesium peroxide(MgO2). You also might want to consider magnesium hydroxide Mg(OH)2 commonly known as "milk of magnesia". Magnesium hydroxide is made by adding magnesium oxides to water. Evaporating the water reverses the process with the result being the white powder of magnesium oxides, suggesting that milk of magnesia might be an economical and readily available source of the magnesium peroxide that Dr. Donsbach recommends. There is also an excellent product called "Oxy-Powder" that you might want to read about.

magnesium oxide(s) + water --> magnesium hydroxide
magnesium hydroxide --> magnesium oxide(s) + water

***

Individuals who have had transplants should not undertake an H2O2 program. H2O2 stimulates the immune system and could possibly cause a rejection of the organ. - Dr. David Williams.

***
Quackwatch Home Page ||| Special Message for Cancer Patients

Oxygenation Therapy:
Unproven Treatments for Cancer and AIDS
By Saul Green, Ph.D.
The cornerstone of oxygenation therapy is the presumption that human disease, including cancer, is caused by a deficit of tissue oxygen. According to proponents, hypoxia results in anaerobic fermentation, a loss of capacity for oxidative detoxification of toxins and metabolic products, and failure of immune killing of invading bacteria and viruses. To restore ability to carry out these functions, oxygenation promoters propose using chemicals they claim will release oxygen in tissue or act as germicides in vivo. Some of the claims are based on the concepts of William F. Koch (1885-1962) [1] and Otto Warburg (1883-1970) [2].

History of Oxygen Therapies
William F. Koch, a Detroit physician, theorized in 1919 that cancer was caused by a metabolic defect brought on by a single toxin produced by an injury or irritation. He proposed that toxins produced during metabolism and by bacteria were normally burned off during oxidation of carbohydrates. If the toxins persisted, they damaged the toxin-burning system and converted a normally present "harmless germ" into a virulent cancer-causing one. To cure cancer, Koch invented an "antitoxin to cancer" which he said was a mixture of an oxidizing catalyst he called glyoxylide (O=C=C=O) and a chemical called l:4 parabenzoquinone. A one-million-fold dilution [3] of this solution was given to patients by injection every six months, to "stimulate all the body's oxidation reactions to cure the cancer and a host of other diseases." Koch never revealed the process for the manufacture of glyoxylide, nor did he show it to exist.

Does Koch's glyoxylide exist? The molecule glyoxylide has been a subject of investigation by chemists including H. Staudinger in 1913 [4] to Berson in 1986 [5]. Recently Sulzle [6] reviewed the literature and considered the theoretical possibilities for the existence of a compound like glyoxylide. He found that all efforts to prepare, isolate, or chemically identify this compound failed. His studies on the theoretical physical chemistry of glyoxylide showed that the substance described by Koch cannot exist in nature. This, along with Jenssen's failure to find anything in Koch's "medicine" [3], confirms the conclusion that the glyoxylide which Koch claims to have invented did not exist.

Otto Warburg professed that the cancer problem could be solved if one could identify a biochemical difference between the energy-producing systems of normal cells (controlled growth) and cancer cells (uncontrolled growth.) His research with tissue slices [7] led to the discovery of oxygen-transferring enzymes in cellular respiration, and for this he won a Nobel Prize (1931). In 1944 he won a second Nobel Prize for identifying the enzymes that transfer hydrogen in metabolism [8]. But his research never showed that oxygen use by normal and cancer cells was different. What he did find was that cancer cells produced lactate from glucose in the presence of oxygen whereas normal cells only produced lactate from glucose in the absence of oxygen. This observation led him to conclude that energy metabolism in cancer cells was defective [9].

By 1960, research had identified nearly all energy-producing metabolic pathways in both normal and cancer cells and showed that energy-producing systems in normal cells were the same as those found in cancer cells [10]. Despite this, Warburg insisted until his death in 1970 that the cause of cancer was "inferior" energy of anaerobic metabolism [9].

Oxygenation proponents follow the lines of Koch and of Warburg. They claim that toxins that adulterate processed foods, the environment, and medications damage the oxidative metabolism of normal cells which then regress into anaerobic metabolism in which an inferior energy is produced, resulting in cancer. Normal functions such as digestion, elimination, and immune function are also claimed to benefit from treatment with pure, all-natural, poison-free nutrients, vitamin and mineral supplements, and oxygen-yielding substances that restore and replenish the oxygen needed by tissues for burning off toxins. Hydrogen peroxide and ozone are the substances recommended. [11-13]

Hydrogen Peroxide
Hydrogen peroxide, H2O2 [14], was discovered in 1818. It is present in nature in trace amounts. Hydrogen peroxide is unstable, it decomposes violently when in direct contact with rough surfaces or traces of organic or particulate matter. Light, agitation, heating, or chemical substances like carbonates, proteins, chlorides, charcoal, and iron all accelerate the rate of hydrogen peroxide decomposition in solution. One volume of 30% hydrogen peroxide solution will yield 100 volumes of oxygen gas when it decomposes. At 30-35 %, so-called "food grade" hydrogen peroxide is caustic, producing severe skin burns. It can start a fire if allowed to dry on a combustible surface.

Among the earliest proponents of the use of hydrogen peroxide as a treatment for degenerative diseases like cancer was Father Richard Willhelm, [15]. In the 1940's, while working with a microbiologist at the Mayo Clinic, he "learned that bacteria can gnaw at the joints, cause inflammatory arthritis, give off calcium waste that cements bones together, lodge in the liver and kidney and form stones, leave hard deposits on walls of arteries, short circuit the energy in the brain, cut off the blood supply to cells and cause a loss of oxidative metabolism." [15] From Koch and Warburg's work he heard that "cancer doesn't like oxygen," and because he knew that hydrogen peroxide gave off oxygen when it decomposed, he concluded that it should be used to treat diseases which were the result of "inadequate oxygen metabolism." Willhelm referred to hydrogen peroxide as "God's given immune system." [15]

Willhelm met Walter Grotz, a retired US postal system employee, in 1982. When Grotz complained about the pain that his arthritic condition was causing, Willhelm suggested that each day for several weeks Grotz drink from l to 7 glasses of pure water to which a few drops of "food grade" 35% hydrogen peroxide had been added. Grotz said that doing this made him pain free, and he became Willhelms disciple. As a result of their travels, spreading word about peroxide, peroxide became popular for many other uses such as misting flowers, disinfecting aquariums, oxygenating garden soil, bathing pets, treating livestock and fowl, and washing vegetables and farm crops [16]. Most often however it was promoted as a treatment for human illness because, as Willhelm put it, "hydrogen peroxide joyfully relieves asthma, arthritis, multiple sclerosis, emphysema, cancer, the common cold, herpes, candidiasis, angina, malaria, gingivitis, tumors, warts, lupus, psoriasis, moles, amoebiasis and hemorrhoids." [l6,17]

Proponents [11,12] also suggested that patients treat themselves at home by drinking hydrogen peroxide, using it for brushing their teeth, enemas, high colonics, or douches, soaking in a bath with it, or massaging it into the skin. Instructions for preparing the peroxide to be drunk are given in newsletters from "health food" companies that sell what is called "food grade" hydrogen peroxide [18]. One proponent states [18] that it takes one week to "clean out" both the "good and bad" flora in the stomach: "When hydrogen peroxide comes in contact with virus and streptococcus (the bad flora) in your stomach, it liberates free oxygen. If your stomach feels queasy after you drink the (peroxide) solution, the peroxide is seeking out and destroying virus and streptococci. The normal flora, the good ones, can then be replaced by eating plain yogurt and health food supplements that contain acidophilus, bifidus and bulgaricus."

Proponents suggest that hydrogen peroxide can also be administered by soaking for 30 minutes each day in half a bathtub of water containing a pint of 35% "food grade" peroxide, by spraying a 3% solution of "food grade" hydrogen peroxide on ones body, massaging it into the skin three times a day, and by rubbing a gel containing 35% "food grade" hydrogen peroxide, glycerin, and Aloe Vera into the skin [18]. Wilhelm describes a "do it yourself" recipe for making hydrogen peroxide pills for those who are unable to drink it. It calls for mixing baking soda and food grade 35% hydrogen peroxide, allowing the mixture to dry overnight and placing the pulverized powder into capsules. The patient takes three pills per day [11].

Another proponent proposes intravenous infusion of hydrogen peroxide as oxidative therapy [l3]. "There is no distinct class of patients that are [sic] best suited for intravenous hydrogen peroxide therapy because of the wide variety of pathological conditions that improve from oxidative detoxification, the oxygenation of hypoxic tissues and the stimulation of the immune system that an intravenous infusion of hydrogen peroxide induces. Specific benefits are seen in patients with peripherovascular, cerebrovascular and cardiovascular diseases, arrhythmias, emphysema, asthma, cancer, multiple sclerosis, rheumatoid arthritis, Parkinson's disease, migraine, cluster and vascular headaches, allergies, and pain. There may even be a reversal of atherosclerosis due to the action of the peroxide on the lipid material in blood vessel walls" [13,19].

In directions for injecting hydrogen peroxide intravenously one is instructed to prepare 100 ml aliquots of sterile l5% hydrogen peroxide infusion solution made from 30% "food grade" hydrogen peroxide and sterile water to be stored frozen in sealed vials. For injection, the stock is diluted with 5% dextrose to give the final 0.075 % product [19].

Ozone
Ozone was discovered and named by Schonbein in l839. It is formed when an electric spark or ultra-violet (UV) light splits an oxygen molecule into two highly reactive oxygen atoms. Each of these combines with intact oxygen to form the tri-atomic ozone, O3. Ozone is one of the most powerful natural oxidizing agents known because of the highly reactive free radicals it generates on decomposition. These free radicals can destroy many natural biological substances [20]. The discovery of inert plastics made ozones medical applications possible. In the late 1930's, German doctors began to use it in experiments on patients who had a variety of infections and wounds [20-22]. Ozone gas might be bubbled directly into the patients blood, it might be bubbled into blood taken from the patient after which the blood would be re-infused, it might be bubbled into a solution to be used in an enema, colonic irrigation, or douche, or it might be pumped directly into the rectum. Except for situations in which ozone was used topically, the determination of effectiveness was depicted by patient testimonials.

When ozone is introduced into blood, it reacts with water in red cells producing hydrogen peroxide. This aqueous decomposition of ozone also produces bactericidal and membrane-damaging free radicals [21]. Ozone used for treatment [24] is prepared by creating an electric spark in a chamber of pure oxygen. The final mixture contains between 0.l and 5.0% ozone, concentrations that are equivalent to from l.0 ppm to 50 ppm ozone in pure oxygen.

Ozone generated this way has a half life of 45 minutes at room temperature, and under ideal conditions of sterility, dryness, and cleanliness, it must be prepared on site each time it is used. A two-hour exposure to 1200 ppm ozone is needed to kill microorganisms on open surfaces and in water [25]. Concentrations of ozone recommended are: for topical treatment of superficial wounds, 70 to 100 ppm; for slow-healing ulcers, between 40 and 70 ppm; and when oxygenating effects are needed to treat diseases associated with hypoxia, from l to 40 ppm [26].

Ozone has been proposed as a treatment for AIDS [24,27-29]. "Results of experiments indicate that medical ozone has the ability to inactivate extra-cellular HIV-l in serum-supplemented tissue culture fluids and to inhibit the growth of HIV-l at concentrations that are benign to cells in tissue culture." However, HIV is susceptible to inactivation by many relatively innocuous compounds, and claims for benefiting AIDS patients are unconfirmed [ 26,30,31].

In 1993 testimony before Senator Harkin's Subcommittee of the Senate Appropriations Committee, Ed McCabe, a promoter of ozone, stated, "644 German ozone therapists successfully treated 384,775 patients with 5,579,238 doses of ozone with no ill effects. Thousands of published medical papers contain proof of ozones effectiveness in vivo. Numerous US physicians have converted hundreds of AIDS patients from HIV sero-positive to HIV sero-negative status using ozone. Help is available to AIDS patients right now but the medical establishment is ignoring it." [31] No evidence for the claims exist in reliable scientific literature.

Critique
Does anaerobic metabolism cause cancer?

In a 1961 monograph [10], Aisenberg reviewed and analyzed the subject of energy metabolism in normal and tumor tissues. He concluded that most carcinogens are not respiratory poisons; most respiratory poisons are not carcinogens; oxygen neither prevents nor inhibits cancer growth; tumor cells grow optimally in tissue culture dishes in atmosphere containing 20% oxygen; tumors grow rapidly in tissues that are well supplied with oxygenated blood; absence of oxygen does not stimulate tumor growth in vitro or in vivo; agents effective against cancer interfere with DNA synthesis, not with aerobic metabolism; tumors do not get a significant amount of their energy from anaerobic metabolism; tumors can and do produce energy by an oxygen-driven metabolism of fats and carbohydrates.

Since the mid 1960s, information amassed has identified cancer initiation, promotion, and progression. Alteration of genetic regulation through DNA damage, oncogene activation, and inhibitor dysregulation give rise to abnormally proliferating cancer cells. There is no evidence of "poisoning" in the respiratory enzyme systems of tumor tissues. Although Warburg discovered some differences in metabolism between normal and cancer cells, research did not bear out what he considered to be the "primary cause of cancer," i.e., the replacement of respiration by fermentation.[7].

How much of an effect can "oxidative therapy" have in treatment of disease?

The transfer of atmospheric oxygen in the lungs to tissues involves oxygen transport from alveoli to hemoglobin in red cells to tissue cells for use in oxidative metabolism. When oxygen is used as a drug, its pharmacological properties must be defined so that the hazards that attend its use can be monitored [32]. Under normal circumstances, each breath of air taken at sea level has a volume of about 500ml. Slightly less than 20% of this is oxygen. The pressure of air at sea level is 760 mm of mercury (Hg), and the partial pressure of oxygen is about l60 mm Hg. When inspired air reaches the alveoli, it mixes with the gases already present. The partial pressure of oxygen in the alveolar sac is about 100 mm of Hg. Since the partial pressure of oxygen in the pulmonary arteries in the alveolar membranes is about 40 mm of Hg, the oxygen in the alveoli diffuses across the alveolar membrane and into the venous blood. There it is taken up by red cell hemoglobin [32].

Under normal conditions, hemoglobin in blood leaving the lungs is 98% saturated with oxygen. The hemoglobin in one liter of blood can carry about 200 ml of oxygen, and about 50 ml of this is extracted each time it passes through tissue capillaries. The metabolism of a normal 60 kg adult requires delivery of between 200 and 250 ml of oxygen each minute [32]. Since the amount of hydrogen peroxide that is infused into a patient during one "oxidative therapy" session, yields a total of 100 ml of oxygen per day, the treatment can make no significant contribution ones oxygen requirements [33].

Is hydrogen peroxide bactericidal and viricidal?

Phagocytosis is the principal mechanism for the removal of pathological bacteria and fungi [34]. Activated phagocytic cells are drawn to the site of infection, attach to the infectious organisms, and ingest them. The killing of the organisms takes place inside the phagocytic cell. Enzymes generate superoxide free radicals which are fused by superoxide dismutase to produce hydrogen peroxide. Hydrogen peroxide oxidizes cellular chloride in the cell to the killing chloride free radical.

Proponents of oxidative therapy propose that hydrogen peroxide kills bacteria because of their low levels of peroxide-destroying enzymes. But there is no evidence of oxygen intolerance in anaerobic organisms. Although proponents allude to a variety of antibacterial, antiviral, and anti-parasitic actions of hydrogen peroxide [13], they admit that no peroxide-related germicidal activity is found when hydrogen peroxide is infused into patients infected with a variety of organisms [19]. The absence of hydrogen peroxide bactericidal activity has been confirmed by independent investigators [35]. For instance, there is no bactericidal when hydrogen peroxide is infused into blood of rabbits infected with peroxide-sensitive E. coli.

Moreover, increasing the concentration of peroxide ex-vivo in rabbit or human blood containing E.coli produced no evidence of bactericidal activity. Lack of effect of high concentrations of hydrogen peroxide was directly related to the presence of the peroxide-destroying enzyme, catalase. To have any effect, high concentrations of hydrogen peroxide would have to be in contact with the bacteria for significant periods of time. But the large amounts of hydrogen peroxide-destroying enzymes normally present in the blood makes it impossible for peroxide to exist in blood for more than a few seconds. One must conclude that hydrogen peroxide introduced into the blood stream by injection or infusion cannot act as a germicide in human blood.

Hydrogen peroxide does participate in the bactericidal processes within activated phagocyte cells. But when it escapes from the cells into the adjacent extra-cellular space during the inflammatory process, it becomes a major contributor to the tissue damage seen in lung disease, malignancies, and hemolysis. The presence of pharmacological concentrations of hydrogen peroxide in the blood is clearly a double-edged sword which can easily cause as much harm as it can cause good [36].

Can infused hydrogen peroxide raise blood oxygen levels?

Hemoglobin in red cells of arterial blood gives up about 25% of its oxygen when it passes through the tissues, so the hemoglobin of the venous blood leaving the tissues is oxygen-poor. When hydrogen peroxide is injected into venous blood, the oxygen released by the action of catalase is taken up by oxygen-poor hemoglobin. When this venous blood reaches the lungs, it is carrying more oxygenated-hemoglobin than normal. Less oxygen from inspired air is required to saturate it. When arterial blood leaves the lungs it is almost fully (98%) saturated with oxygen and so it becomes impossible for the intravenous infusion of hydrogen peroxide advocated by "oxygenation" proponents to further increase the amount of oxygen carried to the tissues.

The infusion of hydrogen peroxide into arterial blood is a completely different situation. A theoretical model [37] predicts the effects of an infusion of a hydrogen peroxide solution into arterial blood. Hemoglobin in arterial blood is already saturated with oxygen, so the oxygen released from hydrogen peroxide would not be taken up by hemoglobin. Therefore it would go into plasma. But the process of solution is slow, so undissolved oxygen gas could linger in the blood as bubbles for as long as 30 minutes. In the model, Johnson used 0.12% peroxide to produce a final level of 0.006 volumes peroxide per 100 ml in rabbit blood. Although this amount of hydrogen peroxide released 3.0 ml of oxygen gas in every 100 ml of arterial blood, most of the gas could be taken up by the small amount of unsaturated hemoglobin (2%) in the arterial blood. If however, the hydrogen peroxide content of the blood was doubled, 6.0 ml of oxygen gas would be generated per 100 ml of blood, and this could not be handled by available hemoglobin. Undissolved arterial oxygen would then create gas embolism. Consistent with this prediction for peroxide levels higher than 0.006 volumes percent, Johnson found that at 0.01 volumes 0.12% peroxide, oxygen gas embolism resulted in complete shut down of capillary blood flow in the treated rabbits. [37]

Can oxygen dissolved in the plasma support metabolic needs?

When little or no unsaturated hemoglobin is present,100 ml of plasma at100 mm of ambient (alveolar) oxygen pressure can hold 0.3 ml of oxygen in simple solution. This means that the total amount of oxygen that could be dissolved in all of the plasma in a 60 kg adult, would be about 20 ml. Since there is no physiologic mechanism by which oxygen dissolved in the plasma can be extracted, and since tissues require 200 to 250 ml of oxygen per minute [28], the 20 ml of oxygen dissolved in plasma can be of little use in relieving tissue hypoxia or for supporting aerobic energy metabolism [14,32,33].

Is ingestion or infusion of hydrogen peroxide safe?

At the end of his paper on how to infuse hydrogen peroxide intravenously, Farr cautions that the capacity of the lungs to allow gas embolism diffusion is limited. A continuous infusion of peroxide that results in 0.01 volume per 100 ml blood can cause an arterial gas embolism and irreversible lung damage [19]. That such adverse reactions do occur is clear from reports in the medical literature. These incidents include: oxygen gas emboli, necrosis and gangrene following peroxide enemas or colonic lavage [37-41,]; emphysema following peroxide mouth wash or gargle [42]; and ulcerative colitis, gas embolism, and emphysema following deep wound irrigation [43-45]. Peroxide ingestion results in respiratory arrest, seizures, gas embolism in the portal circulation, shock, and acute hemolysis. [46-48] Stroke and multiple cerebral infarcts [49] and venous embolism follow irrigation of anal fistula and irrigation of surgical wounds [20]. In contrast, the literature published by proponents of oxygenation therapy contain no report of adverse clinical incidents resulting from ingestion or infusion of hydrogen peroxide.

Is ozone effective against HIV?

In 1991, Wells et al [25] reported that gaseous ozone inactivated cell-free HIV-l in cell-free culture medium. Using escalating concentrations of ozone, they showed that a l200 ppm dose delivered into the solution for two hours, reduced the number of infectious viruses by about l011 and reduced detectable virions about 85%. However, there was also a significant reduction in infectivity after virus exposure to nitrogen. Other factors influencing the rate and degree of inactivation of HIV-I by ozone were protein and plasma components in the culture medium. (HIV is known to be inactivated by a host of relatively inactive substances.) While ozone might be useful in rendering commercial blood products free of infectious organisms, more extensive analyses of the HIV-I life cycle was needed before ozone's usefulness as an in vivo anti-retroviral agent could be defined. Poiesz, Wells' co-author, wrote, " No further in vitro work has been done and to my knowledge no in vivo work has been done." [50]

Carpendale and Freeberg [28] studied the effect of 4 ppm ozone on HIV-l suspensions in vitro. Ozone was rapidly degraded by serum components in the culture medium. They theorized that the virus inactivation must have been caused by unknown ozone reaction products. Reaction products of ozone and fatty acids called ozonides have been studied, and some are known to mimic the cellular effects of ozone [51,52]. But Carpendale et al did not report on the effects of ozonides on HIV in suspension.

Does autohemotherapy kill or inactivate HIV-I ?

Ozone has been used to treat infections for nearly 50 years. For the most part the treatments were based on impressions from uncontrolled anecdotal clinical experiences reported in German newspapers, magazines, and proponent newsletters. With the coming of the AIDS pandemic in the 1980s, some physicians offered ozone treatment. Organizations began promoting the medical use of ozone at international meetings. The majority of the papers presented at these meetings referred to the germicidal activity of high concentrations of ozone in vitro, but no convincing evidence was presented that autohemotherapy with ozone at concentrations ranging from 0.l to 5.0 ppm had an effect against HIV in AIDS patients.

In 1991, Garber et al [53] carried out the first well controlled clinical study of auto-hemotherapy for AIDS. These investigators first tested for safety in a Phase I trial and found no toxicity after 12 weeks of treatment. In the Phase II trial which followed, AIDS patients were entered into a randomized, placebo-controlled, double-blinded program designed to compare the effects of unprocessed or ozone-enriched blood infused intermittently over a period of 8 weeks. All patients had CD-4 T-cell counts between 200-400 cells/ul. The results showed that ozonated blood produced no significant hematologic, biochemical, or clinical toxicological effects when compared with controls. CD-4 T-cell counts, interleukin 2, gamma interferon, beta-2 microglobulin , neopterin, and p-24 antigen were unaltered. These results have been replicated and confirmed by independent investigators [54].

In May 1995, the 12th World Congress of the International Ozone Association convened in Lille, France. Of the 42 papers presented, none addressed the effectiveness of autohemotherapy in the treatment of AIDS [55]. In August, 1995, Prof. V. Bocci, one of the organizers of that meeting, wrote:

My positon is based on theoretical grounds that ozone autohemotherapy may be useful only because there is no valid alternative. From a practical point of view I have great difficulty organizing clinical trials. I have frequently expressed my deep concern over the irresponsible, uncontrolled, and unscrupulous information that is being spread around. You must understand that I am not responsible for what is being done or said by people in the U.S. Personally, my interest is in investigating whether properly performed autohemotherapy can be useful for the treatment of chronic viral diseases and other pathologies. As of this time there is no evidence of its validity [56].

In reviewing the clinical histories of AIDS patients who were being treated with ozone, H. S. Fuessl, leading German AIDS specialist [57], states:

After observing ozone treated AIDS patients for long periods of time, we noted that patients who had just started on the ozone therapy showed some increases in CD-4 T-cell counts. But a few weeks later their CD-4 T-cell counts not only returned to their original low levels but in many cases went lower as the clinical picture clearly worsened. Two patients died before our eyes from opportunistic infections soon after beginning the ozone therapy. Those of us who treat HIV infected patients on a daily basis recognize that monitoring the changes of the CD-4 T-cell counts over a short period of time, does not accurately reflect the effect of the treatment or the prognosis of the patient. After following a number of AIDS patients that were receiving ozone therapy, I recognized that increases in the CD-4 T-cell counts could occur in any patient, at any time. But it did not mean that HIV was being killed or that the infection was being arrested. In spite of this knowledge, CD-4 T-cell counts are still the primary diagnostic and prognostic tools used by ozone therapists. (translated from the German by S. Green)

Is autohemotherapy approved by German medical authorities?

Autohemotherapy proponents refer to the widespread use of this treatment in Germany, implying that it is sanctioned by the German medical establishment. Dr. Barbara Burkhard of the Medical Office of Patients Insurance-Bavaria (Munich, Germany) writes, "Ozone therapy is not approved by the medical establishment in our country. The National Health Insurance (Gesetzliche Krankenversicherung) is not allowed to pay for it. In the book of laws on this subject (Sozial Gesetzbuch V), the obligations for insurance institutions are fixed. They are only required to pay for methods that are in accordance with generally accepted medical knowledge and which have made proven contributions in medicine. Doctors who have contracts with health insurance companies only get reimbursement for treatments that are approved by the Bundesausschub der Artz und Krankenkassen. This committee is governed by social insurance regulations and issues the rules for diagnostic and therapeutic medical methods. In an Appendix to their book of rules, methods not approved are listed. Ozone therapy is number 3 on that list." [58]

Are there adverse effects of the use of autohemotherapy?

As of 8/14/1995, a search of the Medline, Health, AIDSline, and Cancerlit databases back to 1966 turned up more than 100 papers citing adverse effects in humans or in experimental animals caused by ozone or ozone reaction products. There were no references to papers in peer-reviewed medical journals that reported beneficial effects when ozone was used as a treatment for viral infections.

How are AIDS patients sold ozone autohemotherapy?

The idea that infusion of ozone-treated blood can cure AIDS patients is being marketed despite is lack of efficacy. This was clear from the testimony of Mr. Ed McCabe, before Senator Harkin's subcommittee of the Committee on Appropriations, U.S. Senate, 1993 [31]. After accusing the medical establishment of intentionally ignoring an effective treatment for AIDS, McCabe declared that he had proof that help is available to AIDS patients right now and that thousands had been successfully treated. But McCabe did not give the Committee references by which his proof could be verified, and he did not identify any of the medical papers he said contained the evidence of autohemotherapy's effectiveness. He showed no proof that US physicians had converted hundreds of AIDS patients from HIV positive to HIV negative status through autohemotherapy; he did not identify how, where, or when he interviewed the "644 German ozone therapists who successfully treated the 384,775 patients with 5,579,238 ozone treatments." He did not provide evidence that autohemotherapy was clinically effective and resulted in long-term benefits.

Summary and Conclusion
Oxygenation therapists proposed that disease is caused by absence of oxygen and loss of cellular ability to use oxygen for "good energy" metabolism, detoxification, and immune system function. Oxygen therapies are proposed in order to restore the body's ability to produce "good" energy, to "detoxify" metabolic poisons, and to kill invading organisms. However, over the five decades that have passed since this concept was proposed, scientists have shown that:

Anerobic energy metabolism (fermentation) is not the cause of cancer.
Koch's glyoxylide does not exist.
Ingestion, infusion, or injection of hydrogen peroxide cannot re-oxygenate the tissues of the body.
Ozone-treated blood infused during autohemotherapy does not kill AIDS virus in vivo.
References
Koch, W.F. The Survival Factor in Neoplastic and Viral Diseases. The Inter. Oxid. Instit., Priest River, Idaho, 83856. 1921.
Warburg, Otto. Cell Physiologist, Biochemist and Eccentric-A Biography by Hans Krebs. Clarendon Press, Oxford. 1981.
Jenssen, W.F. Analysis of Koch Medicines. Anal. Chemist. 50:197A:1978.
Standinger H, Anthes E. Hypothetical molecule, ethendione. Ber Deutch Chem Ges 46:1426, 1913.
Birney DM, Berson JA. Theoretical calculations on glyoxylide. Tetrahedron 42:1561, 1986.
Sulzle D, Weiske T, Schwarz H. Experiments aimed at generating he long sought after glyoxilide by neutralization-reionization mass spectromtry. Int J. Mass Specctroscopy and Ion Processes 125:75, 1993.
Warburg, Otto. Ueber den Stoffwechsel der Tumoren. Springer, Berlin Translated by F. Dickens. Constable, London. 1936.
Warburg, Otto. The Catalytic Activity of Living Tissues. Springer, Berlin 1938.
Warburg, Otto. A Review. Science; l23:309-315:1956.
Aisenberg, A. The glycolysis and respiration of tumors. A Review. Academic Press , NY and London. 1961.
Borell G. The Peroxide Story-2nd Printing. ECHO. 1986.
Le Beau, C. Hydrogen Peroxide Therapy- New Hope for Incurable Disease. 3rd. Edition, revised.
Farr, C.H. Physiological and Biochemical Responses to Intravenous Hydrogen Peroxide in Man. J. Adv. Med. l:ll3-l29:1988.
Merck Index. llth Edition: p. 4725.
Personal Communication from Fr. Richard Willhelm. Enlightened Catholic Health Organization (ECHO). Naples, Florida. 1989.
Newsletter, The Oasis Purewater Company, San Diego, CA. 1988
Peroxide for Improved Health by T. Valentine, an interview with Fr. Richard Willhelm, SPOTLIGHT, August, 1986.
Donsbach, K. Nutrition in Action- A Newsletter. 2:1986. Distributed by Remco of Arizona Inc. Tucson.
Farr, C.H. A protocol and guidelines for safe IV administration of hydrogen peroxide. International Bioxidative Medicine Foundation, Dallas, Texas, 1987
Shah, J. Pedemonte, M.S. and Wilcock, M.M., Hydrogen peroxide may cause venous oxygen embolism. Anesthesiolgy. 6l:631-2:1984.
Ozone and Other Photochemical Oxidants: A Medical and Biologic Review of Environmental Pollutants. Committee of the N.R.C and the N.A.S. 1977.
Bocci, V. Ozonization of Blood for the Therapy of Viral Diseases and Immunodeficiencies. A Hypothesis. Medical Hypotheses. 39:30-34:1992.
Majchrowicz, M,A. Ozone/Oxygen- Treatment Education Program-AIDS Project. Los Angeles, CA 1994.
Carpendale, M.T.F., and Griffis, J. In: Ozone in Medicine. Proc. llth Ozone World Congress. 1993.
Wells, K.H., Latino, J. Gavalchin, J, and Poiesz, B.J. Inactivation of human immunodeficiency virus type I by ozone in vitro. Blood. 78:l882+l890:1991.
McCabe, E., Ozone Therapy for AIDS. AIDS Patient Care. p.254-255, Dec. 1992.
Internat. Ozone Assn. Pan American Committee, Stanford, CT.1993.
Carpendale, M.T.F. and Freeberg, J.K. Ozone inactivates HIV noncytoxic concentrations. Antiviral Res. l6:(199) 281-292:1991.
Carpendale, M.T.F. Does ozone alleviate AIDS diarrhea. J. Clin. Gastro. l7: 2: l42-l45: 1993.
Kief, H., Treatment of Viral Disease with Ozone. Erfahrungsheilkunde, 37:3:1988.
Alternative Medicine: A Hearing Before the Subcommittee of the Committee on Appropriations. US Senate, l03rd Congress, First Session, 1993. Senator Tom Harkin, Chairman.
Comroe, J.H. Jr., Drips R.D. A Monograph: The Physiological Basis for Oxygen Therapy. Charles C Thomas, Springfield Ill. 1950.
Moran, R.F. Oxygen saturation, content and the dyshemoglobins. Pt I. Ciba-Corning News, p.ll, January 1990.
Zinsser Microbiology, 18th Edition. Joklik, Willet, Amos. eds. Appleton, Century-Croft, Norwalk, Ct. 1984.
Shenep, J.L. Stokes, D.C, Hughs W.T. Lack of antibacterial activity after i.v. hydrogen peroxide infusion in experimental E. coli sepsis. Infect. and Immunity. 48:#3:607:1985.
Clifford, D., and Repine, J.E., Hydrogen peroxide mediated killing of bacteria. Mol. and Cellular Biochem. 49:l43-l49:;982
Johnson, R.J.R., Froese, G., Khodadad, M. and Gibson, D. Hydrogen peroxide and radiotherapy. Bubble formation in the blood. Brit. J. Radiol. 41:749: 1968.
Ludington, L.G., Hartman S.W., Keplinger, J.E. and Williams, F.S. Incomplete rupture of the colon following a hydrogen peroxide enema. Arch. Surg. 76:658-66l:1958.
Sellers, R.D., Reventos, J., Lillehei, R.C. and Lillehei, C.W. Cardiac arrest due to use of hydrogen peroxide with experimental study of effects of topical antibacterial agents upon the heart. Jour. Thoracic Cardiovasc. Surg. 44:l4-20:1962.
Shaw, A. Cooperman, A. and Fusco, J. Gas embolism produced by hydrogen peroxide. N.E.J.M. 277:238:1967.
Brodeur, A.E. Peroxide Lavage of Colon in Children Held Risky. Med. Tribune 7:1: Oct.1966.
Walker, J.E.G. Emphysema of soft tissues complicating endodontic treatment using hydrogen peroxide. Brit. Journ of Oral Surg l3:98-99: 1975.
Meyer C.T., Brand, M. Deluca, V.A. and Spiro, H., Hydrogen peroxide colitis: A report of three patients. J. Clin Gastro.3:31-35:1981.
Bassan, M. M. and Dudai, M. Shalev, O. Near fatal systemic oxygen embolism due to wound irrigation with hydrogen peroxide. Post Grad. Med. Journ 58:448-45l:1982.
Sleigh, J.W., Linter, S.P.K., Hazaards of hydrogen peroxide. Br. Med. Journ. 291:l706:1985.
Giberson, T.P., Kern, J.D., Pettigrew, D.W. Eaves, C.C. Haynes J.F. Near fatal hydrogen peroxide ingestion. Ann. Emergency Med.l8:778:1989.
Rackoff, W.R. and Merton, D.F. Gas embolism after ingestion of hydrogen peroxide. Pediatrics. 85:593-594:1990.
Jordan, K.S., Mackey, D. and Garvey E. A case review; acute hemolytic crisis secondary to i.v. injections of hydrogen peroxide. J. of Emerg. Nursing l7:8-10:1991.
Sherman, S.J. Boyer, L.V., Sibley, W.A. Cerebral infarction immediately after ingestion of hydrogen peroxide solution. Stroke.25:l065-l067:1994.
Poiesz, B. Personal communication to S. Green, 8/ 24/1995.
Rietjens, I.M.C.M., Lemmink, H.H., Alink, G.M., Van Bladeren, P.J. The role of glutathione-S-transferases in fatty acid ozonide detoxification. Chem. Biol. Interactions. 62: 3-14: 1987.
Cortesi, R. and Privett, O.S. Toxicity of fatty ozonides and peroxides. Lipids. 7:715:1972.
Garber G.E. Cameron D.W., Hawley-Foss, N. Greenway, D. and Shannon, M.E. The use of ozone treated blood in the therapy of HIV infection and immune disease; a pilot study of safety and efficacy. AIDS. 5:981-984:1991.
Hooker, M.H. and Gazzaard, B.G. Ozone treated blood in the treatment of HIV infection. AIDS. 6:l3l:1991.
Ozone in Medicine: Special Session, Programme -- May 1995. 12th World Congress of the Intern. Ozone Assn. Lille, France.
Bocci, V. Personal communication to S. Green 8/30/1995.
Fuessl H.S. Ozone for AIDS. Z. Allg. Med. 67:1334-1336:1991.
Burkhard, B. Personal communication to S. Green, 5/23/1995.
Vedhara, K., Nott K.H. and Richards S.M. Individual reliability of CD-4 cell counts. AIDS. 9:#1:98-99: 1995.
About the Author
Dr. Green is a biochemist who did cancer research at Memorial Sloan-Kettering Cancer Center for 23 years. He consults on scientific methodology and has a special interest in unproven methods. He can be reached at (212) 957-2029.

Copyright Notice
The original version of this article was published in the Spring/Summer 1998 issue of the Scientific Review of Alternative Medicine. (© 1997 Prometheus Books, all rights reserved).


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